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View Structure Prediction Details

Protein: gdi1
Organism: Schizosaccharomyces pombe
Length: 440 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gdi1.

Description E-value Query
Range
Subject
Range
gi|13936441 - gi|13936441|gb|AAK49815.1|AF251042_1 rab GDP dissociation inhibitor alpha [Mus musculus]
478.0 [0..1] [440..1]
gi|217418277 - gi|217418277|gb|ACK44281.1| GDP dissociation inhibitor 1 (predicted) [Oryctolagus cuniculus]
GDIA_RAT - Rab GDP dissociation inhibitor alpha OS=Rattus norvegicus GN=Gdi1 PE=1 SV=1
478.0 [0..1] [440..1]
gi|238566800, gi... - gi|240849331|ref|NP_001155343.1| GDP dissociation inhibitor 1 [Ovis aries], gi|238566800|gb|ACR46634...
GDIA_BOVIN - Rab GDP dissociation inhibitor alpha OS=Bos taurus GN=GDI1 PE=1 SV=1
477.0 [0..1] [440..1]
GDIA_CANLF - Rab GDP dissociation inhibitor alpha OS=Canis lupus familiaris GN=GDI1 PE=2 SV=1
476.0 [0..1] [440..1]

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Predicted Domain #1
Region A:
Residues: [1-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEEYDVIVL GTGLTECVLS GLLSVDGKKV LHIDRNDYYG ADSASLNLTQ LYALFRPGEQ  60
   61 RPESLGRDRD WCVDLVPKFL MANGDLTNIL IYTDVTRYIE FKQIAGSYVY RDGRIAKVPG 120
  121 NEMEALKSPL MSLFEKRRAK KFLEWVNNYR EDDPSTYKDI NIDRDSMESV FKKFGLQSGT 180
  181 QDFIGHAMAL YLDDAYLKKP ARETRERILL YASSIAKFGK SPYIYPLYGL GELPQGFARL 240
  241 SAIYGGTYML NQPVDEIVYG DDGVAIGVRS GDQVAKAKQI IGDPSYFREK VRSVGRLVRA 300
  301 ICILNHPIPN TDNLDSVQII IPQNQVKRKH DIYIAGISSV HNVCPKGYYL AIISTIVETA 360
  361 NPLSEIAPGL KLLGPVVESF SRVQEIYEPV TDGTKDQCYI SKSVDATSHF ETLTCDVRDI 420
  421 YKRMTGTDLV LKQRPKMEDQ 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 122.0
Match: 1ukvG
Description: Structure of RabGDP-dissociation inhibitor in complex with prenylated YPT1 GTPase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
small GTPase regulator activity 1.82777033221452 bayes_pls_golite062009
GTPase regulator activity 1.69589677829425 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 1.67690582043816 bayes_pls_golite062009
binding 1.28745887296004 bayes_pls_golite062009
enzyme regulator activity 1.00883251592654 bayes_pls_golite062009
amine oxidase activity 0.93095855430028 bayes_pls_golite062009
GDP-dissociation inhibitor activity 0.387378304822822 bayes_pls_golite062009
protein binding 0.347133050347128 bayes_pls_golite062009
transporter activity 0.0442116448779152 bayes_pls_golite062009
antioxidant activity 0.0209903577090486 bayes_pls_golite062009
transcription regulator activity 0.00424758775661527 bayes_pls_golite062009

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