YRC Public Data Repository - Protein Structure Prediction

Protein:	vht1
Organism:	Schizosaccharomyces pombe
Length:	568 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vht1.

Description	E-value	Query Range	Subject Range
gi\|67668083, gi\|... - gi\|67668083\|ref\|ZP_00465278.1\| General substrate transporter:Major facilitator superfamily [Burkhold...	236.0	[0..17]	[537..977]
gi\|49527412 - gi\|49527412\|emb\|CAG61052.1\| unnamed protein product [Candida glabrata] gi\|50291337, gi\|... - gi\|50291337\|ref\|XP_448101.1\| unnamed protein product [Candida glabrata], gi\|49527412\|emb\|CAG61052.1\|...	233.0	[0..16]	[541..53]
gi\|67903516, gi\|... - gi\|67903516\|ref\|XP_682014.1\| hypothetical protein AN8745.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	229.0	[0..44]	[564..2]
HXT5_YEAST - Probable glucose transporter HXT5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HXT5 P... HXT5 - Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable ca... gi\|190405875 - gi\|190405875\|gb\|EDV09142.1\| low-affinity glucose transporter [Saccharomyces cerevisiae RM11-1a] gi\|151944042 - gi\|151944042\|gb\|EDN62335.1\| hexose transporter [Saccharomyces cerevisiae YJM789]	228.0	[0..3]	[562..7]
orf19.2020, orf1... - HGT6 CGDID:CAL0004351 Assembly 19, Contig19-10139 (66413, 64761) CDS, reverse complemented, translat... gi\|68472555, gi\|... - gi\|68472808\|ref\|XP_719469.1\| potential hexose transporter [Candida albicans SC5314], gi\|68472555\|ref...	222.0	[0..31]	[563..1]
KHT2_KLULC - Hexose transporter 2 OS=Kluyveromyces lactis GN=KHT2 PE=3 SV=1	220.0	[0..24]	[561..2]
gi\|52352523 - gi\|52352523\|gb\|AAU43755.1\| GAL2 [Saccharomyces mikatae IFO 1815]	216.0	[0..15]	[561..4]

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Predicted Domain #1

Region A:
Residues: [1-568]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEWPETSR ASSVEENPKL NIPEIVESVS DSKPSLKNQF STTVIDSSDL NVFNDGAETT  60
   61 VKEQEFTSSE LRRLQKLRLK MDLRIIPCLW ILYFLSCCLR FTVSLSFTMN TAQGHSLIQT 120
  121 LSGYSAHYLA LGLALFYVGY IIFEVPSNLM MAFIEPRIWV SRIQLTIGVV GACHAVLGTK 180
  181 HGNAQSYVAL RFFLGVAESG LWPGLAYYMS RWYRGKHLGK RIGWYYTAAQ IAAAAVSLVS 240
  241 AGFQKMDGAR GLYGYQWMFL IWGVVAIAQA LSIPWWLPAV ASKEHRKSLS SFIPLPKWMK 300
  301 TLSPQRIGFL TPADKSLHSR YIAEMNVGKR WQWSDLLKSC LDLRVWPFIL MYFGIVGVGN 360
  361 GIFNYCTLII EEINPSFSGI DISLLNAPIW LADALGIVTV MPLYDRFHKK FSFFTGSCLI 420
  421 IIAGLAVANY APRAWSRYGG LLMIGFGLGP TVPICMAWCS ASMAKTYGDV GVASSLALVT 480
  481 GLGNLGSVVT TYALYSGWPG DPTFRKSNDV CIALIGVSII ACGIEFLLDK TGFGQFNASF 540
  541 NNHDHEVEDE QEMTDIKPAL PSSQQADA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.69897
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
substrate-specific transmembrane transporter activity	5.46247398538901	bayes_pls_golite062009
ion transmembrane transporter activity	4.58978526526921	bayes_pls_golite062009
transporter activity	4.09176719149278	bayes_pls_golite062009
anion transmembrane transporter activity	3.94605227012838	bayes_pls_golite062009
cation transmembrane transporter activity	3.88180006470231	bayes_pls_golite062009
substrate-specific transporter activity	3.59744164024479	bayes_pls_golite062009
transmembrane transporter activity	3.5865018981083	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	2.52916479889426	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.15783210522667	bayes_pls_golite062009
active transmembrane transporter activity	1.59419818573076	bayes_pls_golite062009
secondary active transmembrane transporter activity	1.22264637452409	bayes_pls_golite062009
binding	1.01584233411372	bayes_pls_golite062009
polyol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.924836669821548	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.812001619402678	bayes_pls_golite062009
symporter activity	0.74591237387473	bayes_pls_golite062009
solute:cation symporter activity	0.74591237387473	bayes_pls_golite062009
phosphate transmembrane transporter activity	0.312628600969375	bayes_pls_golite062009
cation:sugar symporter activity	0.143419068761182	bayes_pls_golite062009
sugar:hydrogen symporter activity	0.143419068761182	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: