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View Structure Prediction Details

Protein: SPAC22F8.05
Organism: Schizosaccharomyces pombe
Length: 891 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC22F8.05.

Description E-value Query
Range
Subject
Range
gi|42552929, gi|... - gi|46122639|ref|XP_385873.1| hypothetical protein FG05697.1 [Gibberella zeae PH-1], gi|42552929|gb|E...
532.0 [0..4] [891..3]
gi|60265773, gi|... - gi|60265773|gb|AAX16015.1| trehalose-6-phosphate synthase [Ginkgo biloba], gi|60265771|gb|AAX16014.1...
526.0 [0..82] [891..13]
TPS7_ARATH - Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 7 OS=Arabidopsis thaliana GN=TPS7 PE...
522.0 [0..82] [890..13]
gi|28926747, gi|... - gi|32408985|ref|XP_324973.1| hypothetical protein [Neurospora crassa], gi|28926747|gb|EAA35713.1| hy...
gi|85115848 - gi|85115848|ref|XP_964949.1| hypothetical protein [Neurospora crassa OR74A]
514.0 [0..4] [889..3]
gi|113533672, gi... - gi|34910846|ref|NP_916770.1| putative trehalose-6-phosphate synthase [Oryza sativa (japonica cultiva...
507.0 [0..93] [890..38]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRQFICSIY LPYTINFHLD ELEGNHESHP AITHQEKVTQ THRDSVKIDD ILTRLSISKS  60
   61 ESGQATPVLT PQLEGMNDYF SLGPSKRTGG SMTPGLGAMS PIPGSGRSSP LYTQPRSRAT 120
  121 SPSRVRQADR FAAPGIGAGA LPIRRKRRD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [150-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLAKSVALFE SARWSVERGV VGNSGLFHAV DAAVRDHGLQ NPLWVGLLGM PTESLSEKTK  60
   61 NAISGALLVK HQSLVVYTSD SNFEGHYNHY CRKILWPSLH YQHNEIFSFF HEESNWDDYV 120
  121 AVNRAFADAL IKNYKTGDTI WVNDYHLLLV PNMVRERIPS AIIGLFIHVS FPSSEVFRCF 180
  181 ARRKELLQGM LGSNLIGFQT EEYKRHFLQS CSRVLYAEST FDRILLDDRY IDVYAHPIGA 240
  241 DPVLVDKWLE NPETLEVKEV LEKRYANLNI FVGCDKMDPI RGIREKLLAF EQFLYDNPEY 300
  301 QKNTILIQTS TFTEEQKEYG VAISDIVTRI NSAFGDFSLD HLPVTILSSD LSYPQYLALL 360
  361 SVADAFIVTS LREGMSLTCH EFILTQRQKK SPLIVSEFIG CASMFSNGAF IVNPWSTLEL 420
  421 SLSMKKALTL STNERNQRYS NCLDVVLTHS ASNWVTGFET KLKKSWTSQQ K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.39794
Match: 1uqtA
Description: Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 11.2045941324603 bayes_pls_golite062009
glucosyltransferase activity 8.25064561355471 bayes_pls_golite062009
UDP-glucosyltransferase activity 8.0463972704113 bayes_pls_golite062009
trehalose-phosphatase activity 7.58500038184065 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 3.70184884300914 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
transferase activity 2.18054407163329 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.13085705769565 bayes_pls_golite062009
carbohydrate phosphatase activity 0.78952375993773 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 0.690032302126686 bayes_pls_golite062009
glycogen phosphorylase activity 0.607220464589157 bayes_pls_golite062009
phosphorylase activity 0.296436712681472 bayes_pls_golite062009
mannosyltransferase activity 0.253888301381021 bayes_pls_golite062009
binding 0.228109337040808 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [621-891]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDFSRLPRFT LNFIGNRYDH AKKRLLILNF DGNAVTWEGR HEFVDFHYGY MVSILSKLIA  60
   61 DDRNIVYIAS CLEEDELESL FMHVPGVGLI AENGCYVLPH YAENVHQSWI RLYKKQQMDW 120
  121 REPLHDIIQY YSERTPGSSL IDHGFAMEFN YVKAENRENG LRSAGELASS INETQHGCRA 180
  181 VPLDGRVLCE PTTISKATAA NYIMTHLIKN PEELDLILVA GNNRTDESVF AWANKSKVSS 240
  241 FTVSMGVGNT EAKAYTDGIP SFFNVLNSLC A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.09691
Match: 1u02A
Description: Crystal structure of trehalose-6-phosphate phosphatase related protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
trehalose-phosphatase activity 3.78859922218487 bayes_pls_golite062009
catalytic activity 1.55296860681783 bayes_pls_golite062009
hydrolase activity 0.385402333062566 bayes_pls_golite062009
phosphatase activity 0.159899259988948 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.103902756538853 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle