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Protein Overview: SPAC22F8.05

General Information:
Name(s) found: SPAC22F8.05 [Sanger Pombe]
Description(s) found:
Found 17 descriptions.
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  • alpha,alpha-trehalose-phosphate synthase [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 891 amino acids

    Gene Ontology:
    Cellular Component: alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: cellular response to stress [IEPLink to PubMed article]
    trehalose biosynthetic process [ISSLink to PubMed article]
    Molecular Function: alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGRQFICSIY LPYTINFHLD ELEGNHESHP AITHQEKVTQ THRDSVKIDD ILTRLSISKS  60
   61 ESGQATPVLT PQLEGMNDYF SLGPSKRTGG SMTPGLGAMS PIPGSGRSSP LYTQPRSRAT 120
  121 SPSRVRQADR FAAPGIGAGA LPIRRKRRDS LAKSVALFES ARWSVERGVV GNSGLFHAVD 180
  181 AAVRDHGLQN PLWVGLLGMP TESLSEKTKN AISGALLVKH QSLVVYTSDS NFEGHYNHYC 240
  241 RKILWPSLHY QHNEIFSFFH EESNWDDYVA VNRAFADALI KNYKTGDTIW VNDYHLLLVP 300
  301 NMVRERIPSA IIGLFIHVSF PSSEVFRCFA RRKELLQGML GSNLIGFQTE EYKRHFLQSC 360
  361 SRVLYAESTF DRILLDDRYI DVYAHPIGAD PVLVDKWLEN PETLEVKEVL EKRYANLNIF 420
  421 VGCDKMDPIR GIREKLLAFE QFLYDNPEYQ KNTILIQTST FTEEQKEYGV AISDIVTRIN 480
  481 SAFGDFSLDH LPVTILSSDL SYPQYLALLS VADAFIVTSL REGMSLTCHE FILTQRQKKS 540
  541 PLIVSEFIGC ASMFSNGAFI VNPWSTLELS LSMKKALTLS TNERNQRYSN CLDVVLTHSA 600
  601 SNWVTGFETK LKKSWTSQQK RDFSRLPRFT LNFIGNRYDH AKKRLLILNF DGNAVTWEGR 660
  661 HEFVDFHYGY MVSILSKLIA DDRNIVYIAS CLEEDELESL FMHVPGVGLI AENGCYVLPH 720
  721 YAENVHQSWI RLYKKQQMDW REPLHDIIQY YSERTPGSSL IDHGFAMEFN YVKAENRENG 780
  781 LRSAGELASS INETQHGCRA VPLDGRVLCE PTTISKATAA NYIMTHLIKN PEELDLILVA 840
  841 GNNRTDESVF AWANKSKVSS FTVSMGVGNT EAKAYTDGIP SFFNVLNSLC A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] MSA 3.126996 View MSA. No confident structure predictions are available.
    2 View Details [150..620] PSI-BLAST 61.39794 Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
    3 View Details [621..891] PSI-BLAST 28.09691 Crystal structure of trehalose-6-phosphate phosphatase related protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
    		•  11.2045941324603 bayes_pls_golite062009
  • glucosyltransferase activity
    		•  8.25064561355471 bayes_pls_golite062009
  • UDP-glucosyltransferase activity
    		•  8.0463972704113 bayes_pls_golite062009
  • trehalose-phosphatase activity
    		•  7.58500038184065 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  3.70184884300914 bayes_pls_golite062009
  • catalytic activity
    		•  2.65148466065976 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.62403914335522 bayes_pls_golite062009
  • transferase activity
    		•  2.18054407163329 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.13085705769565 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  0.78952375993773 bayes_pls_golite062009
  • UDP-N-acetylglucosamine 2-epimerase activity
    		•  0.690032302126686 bayes_pls_golite062009
  • glycogen phosphorylase activity
    		•  0.607220464589157 bayes_pls_golite062009
  • phosphorylase activity
    		•  0.296436712681472 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.253888301381021 bayes_pls_golite062009
  • binding
    		•  0.228109337040808 bayes_pls_golite062009
    3
    Term Confidence Notes
  • trehalose-phosphatase activity
    		•  3.78859922218487 bayes_pls_golite062009
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • hydrolase activity
    		•  0.385402333062566 bayes_pls_golite062009
  • phosphatase activity
    		•  0.159899259988948 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.103902756538853 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.65

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle