| Protein: | tpr1 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 1039 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tpr1.
| Description | E-value | Query Range |
Subject Range |
|
|
392.0 | [0..27] | [932..87] |
|
|
361.0 | [0..8] | [977..74] |
|
|
357.0 | [0..1] | [1039..1] |
|
|
351.0 | [0..2] | [1007..521] |
|
|
337.0 | [0..12] | [922..85] |
|
|
337.0 | [0..3] | [1010..580] |
|
|
325.0 | [0..8] | [903..151] |
|
Region A: Residues: [1-261] |
1 11 21 31 41 51
| | | | | |
1 MEGFTLETHA SRIIEVPLLG QEDQSVEIDC SSLPSDATEL CEILVNEQAP REFWTKFAHE 60
61 YYIRGLREQA ILILKSGLET LKDSESLCIL NANIAAIYLS MAREAMLKKD TDLRDEQLRN 120
121 VRTYLEAANN IDSKSEINVL LHGIYRILLN PTDKESLENA ARCFDFVLQK SGGNILGFLG 180
181 KARILYAKGN YRSALKLYQR ALVSNPQFKP DPRIGIGLCF WNLDMKTDAL SAWTRVQQLD 240
241 PKNTVVDTYI GLYYYDLAFQ N
|
| Detection Method: |  |
| Confidence: | 44.39794 |
| Match: | 1w3bA |
| Description: | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [262-508] |
1 11 21 31 41 51
| | | | | |
1 VNNDSFVQNY GKALQHIQRA FKTRNNDPVA SSILERYVYS KKNYEGCIKL AENVIQNSFS 60
61 SSLIADGYYW MGRAYHQMGN NEKAMASYQK AKAADDRHLL SSVGIGQIQI LQNDLTSAKL 120
121 TFERIAEQNQ SCFEALVVLG CLHASDSKPD LTKARMLLDR AFNLVGSSKL PRVVDSDLYI 180
181 TQARLWEKED TKKSLGFLTR ALDFLESAHM SVGPELLNNI AVLQYHLGLI PEAHGNIIKA 240
241 KSVLPDA
|
| Detection Method: | |
| Confidence: | 7.09691 |
| Match: | 2c2lA |
| Description: | Crystal structure of the CHIP U-box E3 ubiquitin ligase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| transcription elongation regulator activity | 5.44222943389468 | bayes_pls_golite062009 |
| RNA polymerase II transcription elongation factor activity | 3.43202137469601 | bayes_pls_golite062009 |
| binding | 2.52126334054344 | bayes_pls_golite062009 |
| transcription regulator activity | 2.36571535004008 | bayes_pls_golite062009 |
| DNA binding | 1.71381351716702 | bayes_pls_golite062009 |
| nucleic acid binding | 1.61516860680687 | bayes_pls_golite062009 |
| protein binding | 1.52807685989528 | bayes_pls_golite062009 |
| transcription factor activity | 1.01338808398786 | bayes_pls_golite062009 |
| transcription factor binding | 0.518146612491969 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.30464889749774 | bayes_pls_golite062009 |
| transcription coactivator activity | 0.116119418380222 | bayes_pls_golite062009 |
| transcription activator activity | 0.0593768116971065 | bayes_pls_golite062009 |
|
Region A: Residues: [509-942] |
1 11 21 31 41 51
| | | | | |
1 NPELSLLLDY NLARCEEELG NTSVASEAYV SILEKHPSFI DARIRKCLLQ LSNPNEETFK 60
61 EIRHIMNADS QNLEVRAFFG WYLSKQKRRP VEDPEVRHCS QTLRHWHDDI YSLVQLGNAY 120
121 MRQAREFRVH NDREKLKRQK LYIKAIQSYD QAIKFDPKNA HAAQGIAIIL AQNRQFSKAL 180
181 LILSKVREAI KDATTLINIG NCLAELKQFS RAIEVFETVY SSTGESDTYG VLSCLGRVWL 240
241 QRGRESKNVD YLKESVRYAT LALEKNPENP SLLFNVAFVQ FQLCELIRQK PENSRTVEDL 300
301 NFAMQQLDAS IETFTKLVSV EHPPYSPTSI EQRAKMAKNT TKRQLERAIQ AQIEYEKSVA 360
361 AKLEDARIQR EKEKARRLAE EEALLKEKQE RERQLQEERQ KMQEEVLEWR KSQQKASEDD 420
421 MSLSDDEEKQ SGKK
|
| Detection Method: | |
| Confidence: | 4.5 |
| Match: | 2gw1A |
| Description: | No description for 2gw1A was found. |
|
Region A: Residues: [943-1039] |
1 11 21 31 41 51
| | | | | |
1 KKKDRKKRKS KSKQESSDSG VSEDDEIPLS DARNKTKKRR VNRRVISEEY TFDQDSDAEG 60
61 NQEEEVSRTI EEKQDNDITD NQDDNKELNL FSEEDEE
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
