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View Structure Prediction Details

Protein: tfb1
Organism: Schizosaccharomyces pombe
Length: 477 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tfb1.

Description E-value Query
Range
Subject
Range
gi|30584247, gi|... - gi|60653005|gb|AAX29197.1| general transcription factor IIH polypeptide 1 62kDa [synthetic construct...
456.0 [0..2] [471..63]
GTF2H1 - general transcription factor IIH, polypeptide 1, 62kDa
gi|168277836, gi... - gi|168277836|dbj|BAG10896.1| TFIIH basal transcription factor complex p62 subunit [synthetic constru...
456.0 [0..2] [471..63]
gi|114636459, gi... - gi|114636461|ref|XP_001173127.1| PREDICTED: general transcription factor IIH, polypeptide 1, 62kDa i...
454.0 [0..2] [471..63]
gi|67972274 - gi|67972274|dbj|BAE02479.1| unnamed protein product [Macaca fascicularis]
454.0 [0..2] [449..63]
gi|57102734 - gi|57102734|ref|XP_534083.1| PREDICTED: similar to TFIIH basal transcription factor complex p62 subu...
452.0 [0..2] [471..63]
gi|86821662, gi|... - gi|86821662|gb|AAI05487.1| General transcription factor IIH, polypeptide 1, 62kDa [Bos taurus], gi|1...
450.0 [0..2] [471..37]
gi|34856117, gi|... - gi|34856117|ref|XP_341864.1| PREDICTED: similar to TFIIH basal transcription factor complex p62 subu...
443.0 [0..2] [471..63]

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Predicted Domain #1
Region A:
Residues: [1-60]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRVFIVVKE GEDPTSLVFH FTGTPNAREN CDMITNELRN AIQRQREGSQ SKPQGANVDR  60
   61 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [61-123]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNSTNLEKDI DLQESLLTNN PDLLQTFKEA VMKGHLSNEQ FWSTRLHLLR AHAVERSQQR  60
   61 GPY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.154902
Match: 2diiA
Description: No description for 2diiA was found.

Predicted Domain #3
Region A:
Residues: [124-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVLSTIKPKT VDNQMKVSLT GQQIHDMFEQ HPLLRKVYDK HVPPLAEGEF WSRFFLSKLC  60
   61 KKLRGDR

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.74
Match: 1x3aA
Description: Solution structure of the BSD domain of human Synapse associated protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [191-267]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITPMDPSDDI MDKYLKDNEE VTKVSDEPIA SHLFDLEGND QNANVIAELR PDITMRIDKE  60
   61 ALPFMKNINQ LSERLLE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [268-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSLGNSKRFN NENEETYLKE SGFHDLEEEA SDSKVVLKIK GQDQLLENNF VPSKNQVGLE  60
   61 PLPSLEALQH LYQEDSISLN HIEHDSDSLA EAAMQLTQSM REKHEFETHG TASNLPIDIK 120
  121 NEIVLCHTVT IEFLHQFWNA LLNTTFPDKK AMAPLQNALL NSKKRVEAIA SQAQEQNVDP 180
  181 KLVYELVSCT LTSIDTSISE YQRRMSYPPA 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.960 0.011 transcription initiation from RNA polymerase II promoter a.63.1 Apolipophorin-III


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle