YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC24C9.09
Organism:	Schizosaccharomyces pombe
Length:	473 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC24C9.09.

Description	E-value	Query Range	Subject Range
SYT_METCA - Threonyl-tRNA synthetase OS=Methylococcus capsulatus GN=thrS PE=3 SV=1 SYT_METCA - Threonine--tRNA ligase OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath) GN=thrS ...	389.0	[0..2]	[464..191]
SYT_METFK - Threonine--tRNA ligase OS=Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875) GN=thrS PE...	387.0	[0..2]	[468..191]
gi\|167620276 - gi\|167620276\|ref\|ZP_02388907.1\| threonyl-tRNA synthetase [Burkholderia thailandensis Bt4] SYT_BURTA - Threonine--tRNA ligase OS=Burkholderia thailandensis (strain E264 / ATCC 700388 / DSM 13276 / CIP 10...	386.0	[0..2]	[473..191]
gi\|148027559, gi... - gi\|254358432\|ref\|ZP_04974705.1\| threonyl-tRNA synthetase [Burkholderia mallei 2002721280], gi\|194575... gi\|254206061, gi... - gi\|254206061\|ref\|ZP_04912413.1\| threonyl-tRNA synthetase [Burkholderia mallei JHU], gi\|194529494\|ref... SYT_BURPS - Threonine--tRNA ligase OS=Burkholderia pseudomallei (strain K96243) GN=thrS PE=3 SV=1 SYT_BURMA - Threonine--tRNA ligase OS=Burkholderia mallei (strain ATCC 23344) GN=thrS PE=3 SV=1 SYT_BURMA - Threonine--tRNA ligase OS=Burkholderia mallei GN=thrS PE=3 SV=1 SYT_BURPS - Threonine--tRNA ligase OS=Burkholderia pseudomallei GN=thrS PE=3 SV=1 gi\|225928297, gi... - gi\|226199711\|ref\|ZP_03795264.1\| threonine--tRNA ligase [Burkholderia pseudomallei Pakistan 9], gi\|22... gi\|237812016, gi... - gi\|237812016\|ref\|YP_002896467.1\| threonine--tRNA ligase [Burkholderia pseudomallei MSHR346], gi\|2375... gi\|238562605, gi... - gi\|238562605\|ref\|ZP_04610138.1\| threonine--tRNA ligase [Burkholderia mallei GB8 horse 4], gi\|2385222... gi\|194525325, gi... - gi\|254199739\|ref\|ZP_04906105.1\| threonyl-tRNA synthetase [Burkholderia mallei FMH], gi\|194525325\|ref... gi\|134246235, gi... - gi\|134282197\|ref\|ZP_01768902.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 305], gi\|1342462... SYT_BURM9 - Threonine--tRNA ligase OS=Burkholderia mallei (strain NCTC 10229) GN=thrS PE=3 SV=1 gi\|167902959 - gi\|167902959\|ref\|ZP_02490164.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei NCTC 13177] SYT_BURMS - Threonine--tRNA ligase OS=Burkholderia mallei (strain SAVP1) GN=thrS PE=3 SV=1 gi\|167894556 - gi\|167894556\|ref\|ZP_02481958.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 7894] SYT_BURM7 - Threonine--tRNA ligase OS=Burkholderia mallei (strain NCTC 10247) GN=thrS PE=3 SV=1 gi\|167919220 - gi\|167919220\|ref\|ZP_02506311.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei BCC215] SYT_BURP6 - Threonine--tRNA ligase OS=Burkholderia pseudomallei (strain 668) GN=thrS PE=3 SV=1 gi\|167911196 - gi\|167911196\|ref\|ZP_02498287.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 112] gi\|167816071 - gi\|167816071\|ref\|ZP_02447751.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 91] SYT_BURP0 - Threonine--tRNA ligase OS=Burkholderia pseudomallei (strain 1106a) GN=thrS PE=3 SV=1 gi\|167738851 - gi\|167738851\|ref\|ZP_02411625.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 14] gi\|167845979 - gi\|167845979\|ref\|ZP_02471487.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei B7210] gi\|167824445 - gi\|167824445\|ref\|ZP_02455916.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 9] gi\|254259413, gi... - gi\|254259413\|ref\|ZP_04950467.1\| threonine--tRNA ligase [Burkholderia pseudomallei 1710a], gi\|2542181... gi\|242141027, gi... - gi\|242317788\|ref\|ZP_04816804.1\| threonine--tRNA ligase [Burkholderia pseudomallei 1106b], gi\|2421410... gi\|167719848 - gi\|167719848\|ref\|ZP_02403084.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei DM98] gi\|167003090, gi... - gi\|243061341\|gb\|EES43527.1\| threonine--tRNA ligase [Burkholderia mallei PRL-20], gi\|167003090\|ref\|ZP... gi\|217423341, gi... - gi\|217423341\|ref\|ZP_03454842.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 576], gi\|2173931... gi\|157806992, gi... - gi\|254297839\|ref\|ZP_04965292.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 406e], gi\|194571... gi\|254180004, gi... - gi\|254180004\|ref\|ZP_04886603.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei 1655], gi\|194506... gi\|254177492, gi... - gi\|254177492\|ref\|ZP_04884147.1\| threonyl-tRNA synthetase [Burkholderia mallei ATCC 10399], gi\|194313... SYT_BURP1 - Threonine--tRNA ligase OS=Burkholderia pseudomallei (strain 1710b) GN=thrS PE=3 SV=1 gi\|254197889, gi... - gi\|254197889\|ref\|ZP_04904311.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei S13], gi\|1945150... gi\|254188582, gi... - gi\|254188582\|ref\|ZP_04895093.1\| threonyl-tRNA synthetase [Burkholderia pseudomallei Pasteur 52237], ...	385.0	[0..2]	[473..191]
gi\|82531244 - gi\|82531244\|ref\|ZP_00890465.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia pseudomallei 1106a] gi\|83623018 - gi\|83623018\|ref\|ZP_00933304.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei JHU] gi\|83678955, gi\|... - gi\|83678955\|ref\|ZP_00940674.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia pseudomallei 406e], g... gi\|82534581 - gi\|82534581\|ref\|ZP_00893613.1\| hypothetical protein Bpse110_02004189 [Burkholderia pseudomallei 1106... gi\|83618149 - gi\|83618149\|ref\|ZP_00928620.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei FMH] gi\|87315477, gi\|... - gi\|87315477\|ref\|ZP_01096505.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei 2002721280], g... gi\|100120652, gi... - gi\|67758563\|ref\|ZP_00497324.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia pseudomallei S13], gi... gi\|85064735 - gi\|85064735\|ref\|ZP_01025588.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei 10229] gi\|67647610 - gi\|67647610\|ref\|ZP_00445850.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei NCTC 10247] gi\|67669281, gi\|... - gi\|99907632\|ref\|ZP_01315504.1\| hypothetical protein Bpse1_03005166 [Burkholderia pseudomallei 1655],... gi\|100918325, gi... - gi\|67638709\|ref\|ZP_00437644.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei 10399], gi\|100... gi\|67641368 - gi\|67641368\|ref\|ZP_00440148.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei GB8 horse 4] gi\|100058794, gi... - gi\|67752815\|ref\|ZP_00491774.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia pseudomallei Pasteur]... gi\|84522847 - gi\|84522847\|ref\|ZP_01009983.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia mallei SAVP1] gi\|90290648, gi\|... - gi\|90290648\|ref\|ZP_01210297.1\| hypothetical protein Bpse17_02004643 [Burkholderia pseudomallei 1710a... gi\|67737810 - gi\|67737810\|ref\|ZP_00488542.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia pseudomallei 668]	384.0	[0..2]	[473..186]
SYT_BORA1 - Threonine--tRNA ligase OS=Bordetella avium (strain 197N) GN=thrS PE=3 SV=1	384.0	[0..2]	[471..196]
SYT_BORPE - Threonine--tRNA ligase OS=Bordetella pertussis GN=thrS PE=3 SV=1 SYT_BORBR - Threonyl-tRNA synthetase OS=Bordetella bronchiseptica GN=thrS PE=3 SV=1 SYT_BORPA - Threonine--tRNA ligase OS=Bordetella parapertussis GN=thrS PE=3 SV=1 SYT_BORPA - Threonine--tRNA ligase OS=Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253) GN=thr... SYT_BORBR - Threonine--tRNA ligase OS=Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50) GN=thr... SYT_BORPE - Threonine--tRNA ligase OS=Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) GN=thrS...	382.0	[0..2]	[471..196]
SYT_BURS3 - Threonine--tRNA ligase OS=Burkholderia sp. (strain 383) GN=thrS PE=3 SV=1 SYT_BURL3 - Threonine--tRNA ligase OS=Burkholderia lata (strain ATCC 17760 / LMG 22485 / NCIMB 9086 / R18194 / 3...	382.0	[0..2]	[473..191]
gi\|84361561 - gi\|84361561\|ref\|ZP_00986224.1\| COG0441: Threonyl-tRNA synthetase [Burkholderia dolosa AUO158]	381.0	[0..2]	[473..174]
gi\|254245609, gi... - gi\|254245609\|ref\|ZP_04938930.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia PC184]... gi\|162218055, gi... - gi\|67656296\|ref\|ZP_00453679.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia AU 1054... gi\|162227933, gi... - gi\|67668173\|ref\|ZP_00465361.1\| Threonyl-tRNA synthetase, class IIa [Burkholderia cenocepacia HI2424]...	381.0	[0..2]	[473..191]

Back

Predicted Domain #1

Region A:
Residues: [1-473]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLKKFQLHT PFAHSCNRVE IYTARFGPTP FSTKANNLKQ PESTLNDHRT IAARQKLYTT  60
   61 SILTPGSIFF LPHGTRIYNR LVDFLRAQYQ IHGFEEIITP LIFKKDLWEK SGHWQNYEKE 120
  121 IFRVEESRNV EDEHSNATYG LKPMNCPGHC IVYASTERSY KELPLRFADF SPLHRNEASG 180
  181 ALSGLTRLRC FHQDDGHIFC SPESIKDEIK NTLTFVKQVY SLLGMNKLKL YLSTRPEEHI 240
  241 GSLDTWNEAE NGLREALQES GETWIINEGD GAFYGPKIDV MVADARGKWH QTATIQLDFN 300
  301 LPQRFKLYYR TDAGDNAGSE KLIKQPVMIH RAIFGSLERF MGILIEHLNG HWPFWLSPRH 360
  361 AVILPVNQTD RILTYAKQVQ KELSNQEVNE SEFLPLNKNT YYVDINAEAQ SIGKRLRESR 420
  421 LLNYNYEIVI GEDEVDKEIL SVSSRHNHNS RDTRKMTIQQ LKKEFIENVK AYR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	1qf6A
Description:	Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming aminoacyl-tRNA and related compounds	7.89468709683036	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.89468709683036	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.88410036819636	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
threonine-tRNA ligase activity	6.47381405106149	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	2.99105702052936	bayes_pls_golite062009
serine-tRNA ligase activity	2.46505535069103	bayes_pls_golite062009
glycine-tRNA ligase activity	2.29229136935761	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
binding	0.966824335333342	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
transcription regulator activity	0.375542987753806	bayes_pls_golite062009
nucleic acid binding	0.281662799812287	bayes_pls_golite062009
protein binding	0.0804954454681041	bayes_pls_golite062009
DNA binding	0.0309732052586011	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: