YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC342.02
Organism:	Schizosaccharomyces pombe
Length:	811 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC342.02.

Description	E-value	Query Range	Subject Range
gi\|34932918, gi\|... - gi\|62663073\|ref\|XP_573963.1\| PREDICTED: glutaminyl-tRNA synthetase [Rattus norvegicus], gi\|56090285\|...	715.0	[0..5]	[808..3]
QARS - glutaminyl-tRNA synthetase gi\|168277804 - gi\|168277804\|dbj\|BAG10880.1\| glutaminyl-tRNA synthetase [synthetic construct] tr\|M0RDR7\|M0RDR7_RAT - Protein LOC100911132 OS=Rattus norvegicus GN=LOC100911132 PE=3 SV=1	715.0	[0..7]	[808..5]
gi\|90076252 - gi\|90076252\|dbj\|BAE87806.1\| unnamed protein product [Macaca fascicularis] gi\|109039732 - gi\|109039732\|ref\|XP_001110256.1\| PREDICTED: glutaminyl-tRNA synthetase isoform 2 [Macaca mulatta]	711.0	[0..7]	[808..5]
gi\|55741703 - ref\|NP_598555.1\| glutaminyl-tRNA synthetase [Mus musculus] gi\|55741703, gi\|... - gi\|74221103\|dbj\|BAE42057.1\| unnamed protein product [Mus musculus], gi\|55741703\|ref\|NP_598555.1\| glu...	707.0	[0..5]	[809..3]
gi\|67970692 - gi\|67970692\|dbj\|BAE01688.1\| unnamed protein product [Macaca fascicularis]	702.0	[0..7]	[808..5]
gi\|73985557 - gi\|73985557\|ref\|XP_533833.2\| PREDICTED: similar to glutaminyl-tRNA synthetase isoform 1 [Canis famil...	697.0	[0..7]	[808..5]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQDYEELRA KFTKIGLNET TVKDTLKNKK LSSSLNKVIE ETNVGSSGCD RTIGNLLFTL  60
   61 ANASLKQKDP KSNAHEAFIA SKIVSGDLKT NLQVNAAITY CKDKDTIDES EFDKETGVGV 120
  121 VLTPEQIEQL VGDYVAENKS KILEQRYQLL NPSASALRQH ALLKWA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	101.769551
Match:	PF04558.6
Description:	No description for PF04558.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [167-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQLEVKQTLD RKFLELLGPK TEQDAAAGKK KGAKAKNSKQ KTVDSGKAKE QKIVSEQSKK  60
   61 YNMFEEGFLA KLHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	1iq0A
Description:	Arginyl-tRNA synthetase (ArgRS); Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [241-811]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGGNTQLIPE RMKEHLQATG GGVVTRFPPE PNGYLHIGHS KAIAVNFGFA RYHNGVCYLR  60
   61 FDDTNPEAEE ERYFESIKDL VAWLGFQPYK ITYSSDYFDK LYELAEELIK RDKAYVCHCT 120
  121 DAEIKKARGG EERGPRYACV HRDRPIEESL LEFRNMRDGK YQPKEAILRM KQDLSDGNPQ 180
  181 MWDLIAYRVL NSPHPRTGDK WKIYPTYDFT HCLVDSFENI SHSLCTTEFI LSRVSYEWLC 240
  241 NALEVYCPAQ REYGRLNVVG TLMSKRKIMK LVKEGYVHGW NDPRLYTLVA LRRRGVPPGA 300
  301 ILEFVSEVGV TTAVSNIEVA RFENCVRKFL ENSVPRLMFL PDPIKVTLEN LDDSYREQIE 360
  361 IPFNPKDPSM GSRSAFLTKH IYIDRSDFRE EASSDFFRLT LGQPVGLFRA SHPVVAKRVV 420
  421 KNDEGEPIEI IAEYDASSSK KPKTFIQWVS RDKESNSPVL IAETRLFNNL FKCDNPAALK 480
  481 EQELAAQLNP ESEVVLKNSI IEPGIYDLIK SAPWPKTDSS AGVDKAENPE SVRFQAMRVG 540
  541 YFCLDEDTKK PNHLVLNRIV SLREDSAKNK N

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	154.0
Match:	1qrtA
Description:	Gln-tRNA synthetase (GlnRS), C-terminal (anticodon-binding) domain; Glutaminyl-tRNA synthetase (GlnRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamine-tRNA ligase activity	7.66556935228325	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
lysine-tRNA ligase activity	4.64665624411373	bayes_pls_golite062009
structural constituent of ribosome	4.61484562096458	bayes_pls_golite062009
structural molecule activity	4.261982318682	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
5S rRNA binding	2.25646775578129	bayes_pls_golite062009
rRNA binding	2.12571610259264	bayes_pls_golite062009
methionine-tRNA ligase activity	2.01261843164558	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
tryptophan-tRNA ligase activity	1.14187887833901	bayes_pls_golite062009
arginine-tRNA ligase activity	1.13743634264647	bayes_pls_golite062009
nucleotidyltransferase activity	1.06535308346284	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.625793556381714	bayes_pls_golite062009
binding	0.47302762432927	bayes_pls_golite062009
nucleic acid binding	0.161799496958314	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: