YRC Public Data Repository - Protein Structure Prediction

Protein:	srb4
Organism:	Schizosaccharomyces pombe
Length:	545 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for srb4.

Description	E-value	Query Range	Subject Range
gi\|39970371, gi\|... - gi\|86196334\|gb\|EAQ70972.1\| hypothetical protein MGCH7_ch7g379 [Magnaporthe grisea 70-15], gi\|3997037...	461.0	[0..1]	[367..7]
MED17_EMENI - Mediator of RNA polymerase II transcription subunit 17 OS=Emericella nidulans GN=srb4 PE=3 SV=1 MED17_EMENI - Mediator of RNA polymerase II transcription subunit 17 OS=Emericella nidulans (strain FGSC A4 / ATCC...	430.0	[0..10]	[431..1]
gi\|32408655, gi\|... - gi\|32408655\|ref\|XP_324808.1\| predicted protein [Neurospora crassa], gi\|28927581\|gb\|EAA36532.1\| predi... gi\|85074801 - gi\|85074801\|ref\|XP_965768.1\| hypothetical protein NCU00628 [Neurospora crassa OR74A]	423.0	[0..14]	[356..20]
MED17_ASHGO - Mediator of RNA polymerase II transcription subunit 17 OS=Ashbya gossypii GN=SRB4 PE=3 SV=1 MED17_ASHGO - Mediator of RNA polymerase II transcription subunit 17 OS=Ashbya gossypii (strain ATCC 10895 / CBS 1...	388.0	[0..34]	[366..82]
gi\|46128327, gi\|... - gi\|46128327\|ref\|XP_388717.1\| hypothetical protein FG08541.1 [Gibberella zeae PH-1], gi\|42548100\|gb\|E...	388.0	[0..13]	[361..7]
MED17_YEAST - Mediator of RNA polymerase II transcription subunit 17 OS=Saccharomyces cerevisiae (strain ATCC 2045... SRB4 - Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form ...	354.0	[0..34]	[362..99]
MED17_ASPFU - Mediator of RNA polymerase II transcription subunit 17 OS=Neosartorya fumigata (strain ATCC MYA-4609... MED17_ASPFU - Mediator of RNA polymerase II transcription subunit 17 OS=Aspergillus fumigatus GN=srb4 PE=3 SV=1	328.0	[0..12]	[446..4]
MED17_ASPTN - Mediator of RNA polymerase II transcription subunit 17 OS=Aspergillus terreus (strain NIH 2624 / FGS...	327.0	[0..10]	[431..1]
gi\|88182179, gi\|... - gi\|88182179\|gb\|EAQ89647.1\| hypothetical protein CHGG_06266 [Chaetomium globosum CBS 148.51], gi\|1161...	325.0	[0..15]	[436..5]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEEANKDAD ISSLSLSLDP EIIGGQNNFL ENNLQQIFQK IIQERGPFRD LKEEDLQKEL  60
   61 QKESIKDESS AKSSETENVL EFATLDSKRN VNDTEVESMD SQAYKKELIE QIMIAQTECS 120
  121 LALDMTSLLL SKFKENSIET ISPFLKSTVP PSSLQFSRSQ PPESKESDAT LAKCWKEKSL 180
  181 TSSCKFLFEA KERLTSVVET EHEYYTELVK VKEASWPLFN SQGSNHLSVQ YSCLGGISLG 240
  241 LGLIRMKPES KSFEVQSSLL YSQAALKISI LNKDRDEIGS STWSWPSQN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [290-368]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CNSVLLKDIY KLQEILFEMD IWNSLLQEAQ SCGNQGVNFT GDEILVPISD DHVVRITLET  60
   61 SSKNTESGFT EDKKSNEDT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.365	0.826	regulation of transcription, DNA-dependent	a.4.5	"Winged helix" DNA-binding domain

Predicted Domain #3

Region A:
Residues: [369-545]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STNFVTIKQE KELLKCLCDT LNAIAHILFL KHCRKSDRRS QQPELYMAID ANAPLILRPL  60
   61 IFYYNLNQES LEFQRWLKQR DISFKFMPNY PWEKAKDFLE LENSLSINRL SISWRIMVSN 120
  121 FEPAIFIQHT PTLHGTDKSV WRCKDQYSSN QFSSLKNVCQ YIEHHINSLS RRSKKTE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits