YRC Public Data Repository - Protein Structure Prediction

Protein:	smn1
Organism:	Schizosaccharomyces pombe
Length:	152 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for smn1.

Description	E-value	Query Range	Subject Range
gi\|39946616, gi\|... - gi\|39946616\|ref\|XP_362845.1\| predicted protein [Magnaporthe grisea 70-15], gb\|EAA49677.1\| hypothetic...	161.0	[0..4]	[146..9]
SMN_BOVIN - Survival motor neuron protein OS=Bos taurus GN=SMN1 PE=2 SV=2	156.0	[0..7]	[150..28]
gi\|40741318, gi\|... - gi\|67528298\|ref\|XP_661951.1\| hypothetical protein AN4347.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	152.0	[0..3]	[146..11]
gi\|31075799 - gi\|31075799\|gb\|AAP42462.1\| survival motor neuron [Canis familiaris]	149.0	[0..7]	[150..23]
gi\|187040106, gi... - gi\|39579756\|emb\|CAE56707.1\| Hypothetical protein CBG24493 [Caenorhabditis briggsae], gi\|187040106\|em...	148.0	[0..3]	[150..11]
gi\|45383718, gi\|... - gi\|45383718\|ref\|NP_989530.1\| survival of motor neuron [Gallus gallus], gi\|13183642\|gb\|AAK15281.1\| su...	145.0	[0..7]	[150..18]
gi\|13259512, gi\|... - gi\|169167330\|ref\|XP_001713783.1\| PREDICTED: hypothetical protein isoform 2 [Homo sapiens], gi\|169167... gi\|114599811 - gi\|114599811\|ref\|XP_001156259.1\| PREDICTED: survival of motor neuron 1, telomeric isoform 3 [Pan tro...	144.0	[0..7]	[150..32]
gi\|16944474 - gi\|16944474\|emb\|CAD11375.1\| conserved hypothetical protein [Neurospora crassa]	144.0	[0..4]	[151..3]
gi\|28917986, gi\|... - gi\|32415319\|ref\|XP_328139.1\| hypothetical protein [Neurospora crassa], gi\|28917986\|gb\|EAA27670.1\| hy... gi\|85082375 - gi\|85082375\|ref\|XP_956906.1\| hypothetical protein [Neurospora crassa OR74A]	142.0	[0..4]	[151..53]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDQSQKEVWD DSELRNAFET ALHEFKKYHS IEAKGGVSDP DSRLDGEKLI SAARTEESIS  60
   61 KLEEGEQMIN QQTETTLEGD THIQQFADNK GLSDEKPETR AAETHQEFME VPPPIRGLTY 120
  121 DETYKKLIMS WYYAGYYTGL AEGLAKSEQR KD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	14.045757
Match:	1g5vA
Description:	Survival motor neuron protein 1, smn
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.44648286398509	bayes_pls_golite062009
transcription regulator activity	2.23645140702533	bayes_pls_golite062009
fibroblast growth factor binding	1.60204549845754	bayes_pls_golite062009
protein binding	1.5379270754946	bayes_pls_golite062009
DNA binding	1.38254179968032	bayes_pls_golite062009
nucleic acid binding	1.29663886491206	bayes_pls_golite062009
transcription cofactor activity	0.85415557686977	bayes_pls_golite062009
transcription repressor activity	0.81676066297927	bayes_pls_golite062009
transcription factor binding	0.77325691466894	bayes_pls_golite062009
transcription factor activity	0.567394926956068	bayes_pls_golite062009
N-methyltransferase activity	0.53946303154276	bayes_pls_golite062009
chromatin binding	0.25107231011304	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.223495463070134	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: