YRC Public Data Repository - Protein Structure Prediction

Protein:	suc22
Organism:	Schizosaccharomyces pombe
Length:	391 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for suc22.

Description	E-value	Query Range	Subject Range
gi\|297449, gi\|44... - pir\|\|S34808 ribonucleoside-diphosphate reductase (EC 1.17.4.1) small chain - fission yeast (Schizosa...	493.0	[0..1]	[391..1]
gi\|50745023 - gi\|50745023\|ref\|XP_419948.1\| PREDICTED: similar to Ribonucleoside-diphosphate reductase M2 chain (Ri...	477.0	[0..26]	[391..692]
gi\|67515571, gi\|... - gi\|67515571\|ref\|XP_657671.1\| hypothetical protein AN0067.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	458.0	[0..6]	[391..15]
gi\|11878241 - gi\|11878241\|gb\|AAG40862.1\| ribonucleotide reductase [Emericella nidulans]	455.0	[0..6]	[391..15]
gi\|82469974, gi\|... - gi\|82469974\|gb\|ABB77235.1\| ribonucleotide reductase small subunit R2 [Aedes aegypti], gi\|157126966\|r...	455.0	[0..4]	[391..12]
gi\|90298511, gi\|... - gi\|90298511\|gb\|EAS28142.1\| hypothetical protein CIMG_09346 [Coccidioides immitis RS], gi\|119174781\|r...	453.0	[0..6]	[391..15]
gi\|114195303, gi... - gi\|115387427\|ref\|XP_001211219.1\| ribonucleoside-diphosphate reductase small chain [Aspergillus terre...	453.0	[0..6]	[391..15]
RRM2 - ribonucleotide reductase M2 gi\|123981920, gi... - gi\|123996753\|gb\|ABM85978.1\| ribonucleotide reductase M2 polypeptide [synthetic construct], gi\|123981...	453.0	[0..28]	[391..40]
RIR2_DANRE - Ribonucleoside-diphosphate reductase subunit M2 OS=Danio rerio GN=rrm2 PE=1 SV=1	450.0	[0..9]	[391..8]

Back

Predicted Domain #1

Region A:
Residues: [1-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLEHLEEFS YPKEHGEEVE YDSEQGVRKI YVKSIKETFN FDNVSEEEKQ EGGDYYLGKK  60
   61 EDELDEVVLR PNPHRFVLFP IKYHEIWQFY KKAEASFWTA EEIDLSKDLV DWDNKLNADE 120
  121 RYFISTVLAY FAASDGIVNE NLLERFSSEV QIPEARCVYG FQIMIENIHS ETYSLLLDTY 180
  181 IREPKEKQRH FDAILTMGSI KAKAKWALRW INDEDSTYAI RLVAFAAVEG IFFSGSFASI 240
  241 FWLKKRGLMP GLTFSNELIC RDEGLHTDFA CLMFSHLKHR PGRKVVEAII VEAVDIEKEY 300
  301 FTDALPVSLL GMNKDLMCQY IEFVADRLLV ALGNDKYYNV TNPFDFMENI SLAGKTNFFE 360
  361 KKVSDYQIAG VMSGTKRAEK DDHTFTIDED F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	120.0
Match:	1jk0A
Description:	Ribonucleotide reductase R2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	12.7205287868529	bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity	12.6679910771829	bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups	12.0783326936172	bayes_pls_golite062009
class I ribonucleotide reductase activity	7.27682621818194	bayes_pls_golite062009
binding	2.38747290927526	bayes_pls_golite062009
nucleic acid binding	1.75581372355926	bayes_pls_golite062009
DNA binding	1.75528223979795	bayes_pls_golite062009
protein binding	1.35559475972187	bayes_pls_golite062009
transition metal ion binding	0.919082601902017	bayes_pls_golite062009
cation binding	0.635432538918818	bayes_pls_golite062009
metal ion binding	0.635432538918818	bayes_pls_golite062009
ion binding	0.628186057553096	bayes_pls_golite062009
catalytic activity	0.197328811494233	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: