YRC Public Data Repository - Protein Structure Prediction

Protein:	SPBC23E6.06c
Organism:	Schizosaccharomyces pombe
Length:	204 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPBC23E6.06c.

Description	E-value	Query Range	Subject Range
RIBAB_AQUAE, RIB... - Riboflavin biosynthesis protein ribBA OS=Aquifex aeolicus GN=ribBA PE=3 SV=1, Riboflavin biosynthesi... RIBBA_AQUAE - Riboflavin biosynthesis protein RibBA OS=Aquifex aeolicus (strain VF5) GN=ribBA PE=3 SV=1	361.0	[0..2]	[203..9]
gi\|220931844, gi... - gi\|89210620\|ref\|ZP_01189007.1\| 3,4-Dihydroxy-2-butanone 4-phosphate synthase:GTP cyclohydrolase II [...	346.0	[0..2]	[203..1]
gi\|78043761, gi\|... - gi\|78043761\|ref\|YP_360305.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [Ca...	343.0	[0..2]	[202..3]
gi\|119766655, gi... - gi\|68546848\|ref\|ZP_00586392.1\| 3,4-Dihydroxy-2-butanone 4-phosphate synthase [Shewanella amazonensis...	343.0	[0..2]	[200..3]
gi\|125972630, gi... - gi\|67874098\|ref\|ZP_00504003.1\| 3,4-Dihydroxy-2-butanone 4-phosphate synthase:GTP cyclohydrolase II [... gi\|196199353, gi... - gi\|196251390\|ref\|ZP_03150060.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase [Clostridium thermocel...	343.0	[0..2]	[201..3]
RIBBA_SYNY3 - Riboflavin biosynthesis protein RibBA OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=ribBA PE=3 ... gi\|7428281 - pir\|\|S75629 GTP cyclohydrolase II (EC 3.5.4.25) / 3, 4-dihydroxy-2-butanone 4-phosphate synthase (EC... GCH2_SYNY3, RIBA... - Riboflavin biosynthesis protein ribBA OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=r...	342.0	[0..1]	[200..1]
gi\|56750133, gi\|... - gi\|56750133\|ref\|YP_170834.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd...	342.0	[0..2]	[200..9]
gi\|17132669, gi\|... - gi\|17231028\|ref\|NP_487576.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd... gi\|25290330 - pir\|\|AI2247 GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase [imported] - Nosto...	341.0	[0..1]	[200..37]
gi\|33861450, gi\|... - gi\|33861450\|ref\|NP_893011.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd...	341.0	[0..2]	[200..24]
gi\|81300241, gi\|... - gi\|81300241\|ref\|YP_400449.1\| bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohyd...	341.0	[0..2]	[200..9]

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Predicted Domain #1

Region A:
Residues: [1-204]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLASIEEAVN DFRDGKFLIV LDDETRENEG DLIIAGCKVT TEQMAFLVRH SSGYVCVPMT  60
   61 GERLDSLEIP MMVDNNEDRM RTAYAVTLDY ANGTTTGISA HDRALTTRQL ANPEVTSPRE 120
  121 FNRPGHIVPL RARDGGVLER DGHTEAAVDL CKLAGLPPVG AICELVREED GLMSRFDDCI 180
  181 SFGKKWGIKV ITIESLKSYI KGRM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.154902
Match:	1tksA
Description:	Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3,4-dihydroxy-2-butanone-4-phosphate synthase activity	7.56167968780416	bayes_pls_golite062009
GTP cyclohydrolase activity	2.51581618679202	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1.92717548101547	bayes_pls_golite062009
cyclohydrolase activity	1.48770406828775	bayes_pls_golite062009
binding	1.05088380360844	bayes_pls_golite062009
nucleic acid binding	0.637633326908211	bayes_pls_golite062009
catalytic activity	0.343636936190038	bayes_pls_golite062009
protein binding	0.291469273637145	bayes_pls_golite062009
DNA binding	0.21448652890147	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: