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Protein Overview: gi|7428281

General Information:
Name(s) found: gi|7428281 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • pir||S75629 GTP cyclohydrolase II (EC 3.5.4.25) / 3, 4-dihydroxy-2-butanone 4-phosphate synthase (EC 5.4.99.-) ribA - Synechocystis sp. (strain PCC 6803) [NCBI NR]
    • Organism: Synechocystis sp.
    Length: 556 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDAIDAALA DIKAGKAVVV VDDENRENEG DLICAAQFAT PALVNFMAVE ARGLICLAMT  60
   61 GDRLDELDLP LMVSKNTDSN QTAFTVSIDA APHLGVTTGI SAEDRARTIQ IAINPVTRPE 120
  121 DLSRPGHIFP LRAKTGGVLK RAGHTEAAVD LSRLAGLYPA GVICEIQNAD GSMARLPELV 180
  181 EYARKYDLKL ISIADLISYR LQHDRFVQRE TICEFPSQFG EFKLYAYRNL LDQTEHIAIV 240
  241 KGDPSEFGQQ PVMVRMHSEC LTGDALGSLR CDCRMQLQAA LKMLENHGLG VVVYLRQEGR 300
  301 GIGLVNKLKA YSLQDLGYDT VEANERLGFP ADLRDYGMGA QMLNDLGVKQ IRLITNNPRK 360
  361 IAGLKGYGLE IVERVPLLIE ANDYNSHYLT TKAEKLGHWL VKNYLLAIAI KFTPNVASAQ 420
  421 QRYEKLEKIR ALLQGTPLMV HEDNRPVAIA LFGKNSLIFH VGLDQNLPSG QPWQKHDHSP 480
  481 YPALVKDFLV QLKQWPDLQA LAFLIAQGKD PMETLQVSLD RENVSFADLT ADALNQWQPQ 540
  541 TVYTYSKQGS GEMTNR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] PSI-BLAST 86.522879 3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
    2 View Details [204..400] PSI-BLAST 81.154902 Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc
    3 View Details [401..556] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
    		•  7.56167968780416 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  2.51581618679202 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  1.92717548101547 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  1.48770406828775 bayes_pls_golite062009
  • binding
    		•  1.05088380360844 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.637633326908211 bayes_pls_golite062009
  • catalytic activity
    		•  0.343636936190038 bayes_pls_golite062009
  • protein binding
    		•  0.291469273637145 bayes_pls_golite062009
  • DNA binding
    		•  0.21448652890147 bayes_pls_golite062009
    2
    Term Confidence Notes
  • GTP cyclohydrolase activity
    		•  4.36867535385235 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  3.7708397651039 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  3.33696578638249 bayes_pls_golite062009
  • catalytic activity
    		•  1.40764037338379 bayes_pls_golite062009
  • binding
    		•  1.32693434551075 bayes_pls_golite062009
  • protein binding
    		•  0.418779722842637 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle