YRC Public Data Repository - Protein Structure Prediction

Protein:	rad1
Organism:	Schizosaccharomyces pombe
Length:	323 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rad1.

Description	E-value	Query Range	Subject Range
gi\|73991708 - gi\|73991708\|ref\|XP_534355.2\| PREDICTED: similar to proliferating cell nuclear antigen [Canis familia...	328.0	[0..1]	[285..206]
PCNA2_DAUCA - Proliferating cell nuclear antigen large form OS=Daucus carota PE=2 SV=1	313.0	[0..1]	[317..1]
PCNA_BOVIN - Proliferating cell nuclear antigen OS=Bos taurus GN=PCNA PE=2 SV=1	303.0	[0..1]	[285..1]
gi\|53600 - gi\|53600\|emb\|CAA37243.1\| unnamed protein product [Mus musculus]	302.0	[0..1]	[285..1]
gi\|60815711 - gi\|60815711\|gb\|AAX36355.1\| proliferating cell nuclear antigen [synthetic construct]	302.0	[0..1]	[285..1]
PCNA_RAT - Proliferating cell nuclear antigen OS=Rattus norvegicus GN=Pcna PE=1 SV=1	302.0	[0..1]	[285..1]
gi\|55651058, gi\|... - gi\|55651058\|ref\|XP_514499.1\| PREDICTED: proliferating cell nuclear antigen isoform 2 [Pan troglodyte... PCNA_MACFA - Proliferating cell nuclear antigen OS=Macaca fascicularis GN=PCNA PE=2 SV=1 gi\|109092793, gi... - gi\|109092795\|ref\|XP_001115756.1\| PREDICTED: proliferating cell nuclear antigen isoform 2 [Macaca mul... ENSCJAT00000041839 - null gi\|208967140, gi... - gi\|61359492\|gb\|AAX41726.1\| proliferating cell nuclear antigen [synthetic construct], gi\|61358193\|gb\|... PCNA - proliferating cell nuclear antigen HGNC:8729\|MIM:17... - cell nuclear antigen	302.0	[0..1]	[285..1]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQAETVCLK QIQSTLRCID FSKECTIEIT SRGLRFAVEE SQSLQAHAFL DKSLFQTFNF  60
   61 QGDSDGDTYM FQTMISPLLQ SLSIYTDGKE RISTSAWDQP TVNIMHKRGV ICKVQYNGPG 120
  121 CPFIWEVEEM AGYATACELL TMECEDDVDI NRLASTLCTK IIMKSNWLYD ALVELDNNMG 180
  181 ENLIIHTSSQ KSTFLLRCVG ALSTTEIEYP NEKSVLESFE TDSENTYSYR FSLIRHALKA 240
  241 LQVGSKVNLR IDENGTLSIQ IMLVGQEGLC TFVDFCIVPL DLVSEDEEED EEEEPAESNQ 300
  301 SDNNVLRNDP NYRGDAETED EDS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.09691
Match:	1axcA
Description:	Prolifirating cell nuclear antigen (PCNA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA-directed DNA polymerase activity	5.01426276108174	bayes_pls_golite062009
DNA polymerase activity	4.9656505576274	bayes_pls_golite062009
DNA polymerase processivity factor activity	3.26999202934887	bayes_pls_golite062009
nucleotidyltransferase activity	3.23598180825386	bayes_pls_golite062009
DNA binding	2.06316167255592	bayes_pls_golite062009
nucleic acid binding	2.02054974752473	bayes_pls_golite062009
binding	1.88302251910664	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.14392061238362	bayes_pls_golite062009
structure-specific DNA binding	0.785542777582287	bayes_pls_golite062009
mismatched DNA binding	0.552326589459571	bayes_pls_golite062009
catalytic activity	0.48077242755678	bayes_pls_golite062009
double-stranded DNA binding	0.457118392479642	bayes_pls_golite062009
protein binding	0.452894757163315	bayes_pls_golite062009
DNA insertion or deletion binding	0.366820812506101	bayes_pls_golite062009
transferase activity	0.345371754708312	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: