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View Structure Prediction Details

Protein: pgk1
Organism: Schizosaccharomyces pombe
Length: 414 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pgk1.

Description E-value Query
Range		 Subject
Range
gi|197099640 - gi|197099640|ref|NP_001127126.1| phosphoglycerate kinase 1 [Pongo abelii]
PGK1_PONPY - Phosphoglycerate kinase 1 (EC 2.7.2.3) - Pongo pygmaeus (Orangutan)
 668.0 [0..1] [413..1]
PGK1_PONAB - Phosphoglycerate kinase 1 OS=Pongo abelii GN=PGK1 PE=2 SV=4
PGK1_MACFA - Phosphoglycerate kinase 1 OS=Macaca fascicularis GN=PGK1 PE=2 SV=3
PGK1_PONPY - Phosphoglycerate kinase 1 - Pongo pygmaeus (Orangutan)
gi|109131308 - gi|109131308|ref|XP_001100787.1| PREDICTED: similar to phosphoglycerate kinase 1 isoform 4 [Macaca m...
 667.0 [0..1] [413..1]
PGK1_PANTR - Phosphoglycerate kinase 1 OS=Pan troglodytes GN=PGK1 PE=2 SV=1
PGK1 - phosphoglycerate kinase 1
gi|146741442 - gi|146741442|dbj|BAF62377.1| phosphoglycerate kinase 1 [Pan troglodytes verus]
gi|168279045 - gi|168279045|dbj|BAG11402.1| phosphoglycerate kinase 1 [synthetic construct]
 667.0 [0..1] [413..1]
gi|61354676 - gi|61354676|gb|AAX41039.1| phosphoglycerate kinase 1 [synthetic construct]
 667.0 [0..1] [413..1]
gi|76650497 - gi|76650497|ref|XP_581328.2| PREDICTED: similar to Phosphoglycerate kinase, testis specific [Bos tau...
 664.0 [0..1] [413..64]
gi|55250521 - gb|AAH86210.1| Unknown (protein for MGC:98689) [Xenopus laevis]
PGK1_MOUSE - Phosphoglycerate kinase 1 OS=Mus musculus GN=Pgk1 PE=1 SV=4
 663.0 [0..1] [413..1]
PGK1_CRIGR - Phosphoglycerate kinase 1 OS=Cricetulus griseus GN=PGK1 PE=2 SV=2
 662.0 [0..1] [413..1]

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Predicted Domain #1
Region A:
Residues: [1-414] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSTKLAIT DVDLKGKNVL IRVDFNVPLD GDRITNNARI VGALPTIKYA LEQQPKAVIL  60
   61 MSHLGRPNGA RVAKYSLKPV AAELSKLLGK PVKFLDDCVG PEVEKACKEA KGGEVILLEN 120
  121 LRFHIEEEGS AKVDGKKVKA DASAVEAFRK SLTSLGDIFV NDAFGTAHRA HSSMVGVDLP 180
  181 RVSGFLMKKE LDYFSKALEN PARPFLAILG GAKVADKIQL IDNLLDKVNR LIICGGMAFT 240
  241 FLKVLNGMKI GDSLFDEAGS KNVESMMAKA KKNNVEVFLP VDFVTADKFD KDAKVGSATA 300
  301 EEGIPDGWMG LDCGPKSSAK FAEVITTSKT IVWNGPAGVF EFDNFAKGTK SMLDACVKTC 360
  361 EAGNVVIVGG GDTATVAKKY GKEDALSHVS TGGGASLELL EGKALPGVVA LSSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1vjcA
Description: Structure of pig muscle PGK complexed with MgATP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoglycerate kinase activity 5.4060222740811 bayes_pls_golite062009
kinase activity 5.10875323814482 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.75644406547116 bayes_pls_golite062009
transferase activity 3.84971620558441 bayes_pls_golite062009
catalytic activity 2.30057758519011 bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor 2.28472985705972 bayes_pls_golite062009
binding 2.00400587462181 bayes_pls_golite062009
ATP binding 1.2270597395465 bayes_pls_golite062009
adenyl ribonucleotide binding 1.19223643201287 bayes_pls_golite062009
adenyl nucleotide binding 1.17740080861612 bayes_pls_golite062009
transcription regulator activity 0.9898248694651 bayes_pls_golite062009
ribonucleotide binding 0.946046256290779 bayes_pls_golite062009
purine ribonucleotide binding 0.943434082819351 bayes_pls_golite062009
purine nucleotide binding 0.936146648259702 bayes_pls_golite062009
nucleotide binding 0.931721122227797 bayes_pls_golite062009
protein binding 0.206093694938779 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle