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Protein Overview: PGK1

General Information:
Name(s) found: PGK1 [HGNC (HUGO)]
Description(s) found:
Found 45 descriptions.
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  • phosphoglycerate kinase 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSNKLTLD KLDVKGKRVV MRVDFNVPMK NNQITNNQRI KAAVPSIKFC LDNGAKSVVL  60
   61 MSHLGRPDGV PMPDKYSLEP VAVELKSLLG KDVLFLKDCV GPEVEKACAN PAAGSVILLE 120
  121 NLRFHVEEEG KGKDASGNKV KAEPAKIEAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVN 180
  181 LPQKAGGFLM KKELNYFAKA LESPERPFLA ILGGAKVADK IQLINNMLDK VNEMIIGGGM 240
  241 AFTFLKVLNN MEIGTSLFDE EGAKIVKDLM SKAEKNGVKI TLPVDFVTAD KFDENAKTGQ 300
  301 ATVASGIPAG WMGLDCGPES SKKYAEAVTR AKQIVWNGPV GVFEWEAFAR GTKALMDEVV 360
  361 KATSRGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 1000.0 Structure of pig muscle PGK complexed with MgATP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoglycerate kinase activity
    		•  5.4060222740811 bayes_pls_golite062009
  • kinase activity
    		•  5.10875323814482 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.75644406547116 bayes_pls_golite062009
  • transferase activity
    		•  3.84971620558441 bayes_pls_golite062009
  • catalytic activity
    		•  2.30057758519011 bayes_pls_golite062009
  • phosphotransferase activity, carboxyl group as acceptor
    		•  2.28472985705972 bayes_pls_golite062009
  • binding
    		•  2.00400587462181 bayes_pls_golite062009
  • ATP binding
    		•  1.2270597395465 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.19223643201287 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.17740080861612 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.9898248694651 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.946046256290779 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.943434082819351 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.936146648259702 bayes_pls_golite062009
  • nucleotide binding
    		•  0.931721122227797 bayes_pls_golite062009
  • protein binding
    		•  0.206093694938779 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle