YRC Public Data Repository - Protein Structure Prediction

Protein:	pka1
Organism:	Schizosaccharomyces pombe
Length:	512 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pka1.

Description	E-value	Query Range	Subject Range
gi\|47213332 - gi\|47213332\|emb\|CAF93963.1\| unnamed protein product [Tetraodon nigroviridis]	369.0	[0..4]	[512..290]
KPCB_DANRE - Protein kinase C beta type OS=Danio rerio GN=prkcbb PE=2 SV=1	361.0	[0..4]	[512..147]
TPK1 - cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients...	358.0	[0..131]	[512..17]
gi\|507141 - gi\|507141\|gb\|AAA19440.1\| cAMP-dependent protein kinase catalytic subunit [Blastocladiella emersonii]	357.0	[0..142]	[512..36]
KPCA_RAT - Protein kinase C alpha type OS=Rattus norvegicus GN=Prkca PE=1 SV=3 gi\|56914 - gi\|56914\|emb\|CAA30266.1\| unnamed protein product [Rattus rattus]	357.0	[0..37]	[512..181]
gi\|60826237 - gi\|60826237\|gb\|AAX36750.1\| protein kinase C alpha [synthetic construct]	356.0	[0..37]	[512..181]
PRKCA - protein kinase C, alpha gi\|190692009, gi... - gi\|254071371\|gb\|ACT64445.1\| protein kinase C, alpha protein [synthetic construct], gi\|190692009\|gb\|A... HGNC:9393\|MIM:17... - kinase C, alpha	356.0	[0..37]	[512..181]

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Predicted Domain #1

Region A:
Residues: [1-84]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTTAVASKG STNVGSSTDT LSTSASLHPS MNAGSVNEYS EQQRHGTNSF NGKPSVHDSV  60
   61 GSDASVSNGH NNHNESSLWT SGIP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.221849
Match:	1ogqA
Description:	Polygalacturonase inhibiting protein PGIP
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [85-440]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KALEEATKSK KPDSLVSTST SGCASAHSVG YQNIDNLIPS PLPESASRSS SQSSHQRHSR  60
   61 DGRGELGSEH GERRSAMDGL RDRHIRKVRV SQLLDLQRRR IRPADHTTKD RYGIQDFNFL 120
  121 QTLGTGSFGR VHLVQSNHNR LYYAIKVLEK KKIVDMKQIE HTCDERYILS RVQHPFITIL 180
  181 WGTFQDAKNL FMVMDFAEGG ELFSLLRKCH RFPEKVAKFY AAEVILALDY LHHNQIVYRD 240
  241 LKPENLLLDR FGHLKIVDFG FAKRVSTSNC CTLCGTPDYL APEIISLKPY NKAADWWSLG 300
  301 ILIFEMLAGY PPFYSENPMK LYENILEGKV NYPSYFSPAS IDLLSHLLQR DITCRY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.30103
Match:	1qcfA
Description:	Hemapoetic cell kinase Hck; Hemopoetic cell kinase Hck; Haemopoetic cell kinase Hck
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [441-512]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNLKDGSMDI IMHPWFRDIS WDKILTRKIE VPYVPPIQAG MGDSSQFDAY ADVATDYGTS  60
   61 EDPEFTSIFK DF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	95.69897
Match:	1fotA
Description:	cAMP-dependent PK, catalytic subunit
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits