YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC17G8.06c
Organism:	Schizosaccharomyces pombe
Length:	598 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC17G8.06c.

Description	E-value	Query Range	Subject Range
ILVD_CLOTH - Dihydroxy-acid dehydratase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 /...	840.0	[0..40]	[595..2]
ILVD_AQUAE - Dihydroxy-acid dehydratase OS=Aquifex aeolicus GN=ilvD PE=3 SV=1 ILVD_AQUAE - Dihydroxy-acid dehydratase OS=Aquifex aeolicus (strain VF5) GN=ilvD PE=3 SV=1	831.0	[0..37]	[596..1]
ILVD_GEOKA - Dihydroxy-acid dehydratase OS=Geobacillus kaustophilus (strain HTA426) GN=ilvD PE=3 SV=1 ILVD_GEOKA - Dihydroxy-acid dehydratase OS=Geobacillus kaustophilus GN=ilvD PE=3 SV=1	828.0	[0..37]	[593..2]
ILVD_BACCN - Dihydroxy-acid dehydratase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391...	828.0	[0..40]	[594..2]
ILVD_SYNJB - Dihydroxy-acid dehydratase OS=Synechococcus sp. (strain JA-2-3B'a(2-13)) GN=ilvD PE=3 SV=1 gi\|86609436 - gi\|86609436\|ref\|YP_478198.1\| dihydroxy-acid dehydratase [Cyanobacteria bacterium Yellowstone B-Prime...	827.0	[0..40]	[595..9]
ILVD_SYNEL - Dihydroxy-acid dehydratase OS=Synechococcus elongatus GN=ilvD PE=3 SV=1 ILVD_THEEB - Dihydroxy-acid dehydratase OS=Thermosynechococcus elongatus (strain BP-1) GN=ilvD PE=3 SV=1	825.0	[0..38]	[595..4]
ILVD_BACC1 - Dihydroxy-acid dehydratase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=ilvD PE=3 SV=2	825.0	[0..40]	[594..2]
gi\|7436855 - pir\|\|S76895 hypothetical protein - Synechocystis sp. (strain PCC 6803) ILVD_SYNY3 - Dihydroxy-acid dehydratase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=ilvD PE=3 SV=1 ILVD_SYNY3 - Dihydroxy-acid dehydratase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=ilvD PE=3 SV...	824.0	[0..38]	[595..4]
ILVD_LEPIN - Dihydroxy-acid dehydratase OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (stra... ILVD_LEPIN - Dihydroxy-acid dehydratase OS=Leptospira interrogans GN=ilvD PE=3 SV=1	823.0	[0..35]	[597..3]
ILVD_LEPBL - Dihydroxy-acid dehydratase OS=Leptospira borgpetersenii serovar Hardjo-bovis (strain L550) GN=ilvD P... ILVD_LEPBJ - Dihydroxy-acid dehydratase OS=Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197) GN=ilvD ...	823.0	[0..37]	[597..5]

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Predicted Domain #1

Region A:
Residues: [1-598]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMFCKLLRCQ NGIASKRAAL SLKGFKTSSI NLVEKKLNKY SETITGPKSQ GASQAMLYAT  60
   61 GLNEEDMKKP QVGIASCWYE GNPCNMHLLD LGRRVKEGVK KAGLTGFQFN TIGVSDGISM 120
  121 GTTGMRYSLQ SREIIADSIE TVMQGQWYDA NVSIPGCDKN MPGCLIAMGR FNRPSIMVYG 180
  181 GSIRAGHSPC QNNAPIDIVS AFQSYGEFIT GKIDEPTRHD IIRHACPGGG ACGGMYTANT 240
  241 MASCAEAMGM TLPGSSSYLA GSPEKFAECE AAGSAIKRLL VDDIKPRDIM TRSAFENAMV 300
  301 LTMTLGGSTN SVLHLIAIAK SVGITLTLDD FQAVSNRTPF IADMKPSGKY VMEDLFAIGG 360
  361 IPSVLKYLHA EGLIDGSNIT VTGKTLAENL RGFKDLAEGQ KIIRPLSNPI KTEGHLRVLR 420
  421 GSLAPEGSVA KITGKEGLNF TGKARVFDAE NDFIAALERG EFKKGEKTVV IIRFEGPKGG 480
  481 PGMPEMLKPS SAIMGAGLGK DVALLTDGRF SGGSHGFLIG HVDPEAQVGG PIALVQDGDV 540
  541 IEINAVKNTL DLMVDEKEMA RRRSVWKAPP LKYQQGTLLK YARNVSTASK GAVTDSLE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	174.0
Match:	2gp4A
Description:	No description for 2gp4A was found.

Predicted functions:

Term	Confidence	Notes
3-isopropylmalate dehydratase activity	5.35660492472618	bayes_pls_golite062009
catalytic activity	1.61959327305722	bayes_pls_golite062009
carbon-oxygen lyase activity	1.16841092671386	bayes_pls_golite062009
hydro-lyase activity	1.13002130445077	bayes_pls_golite062009
lyase activity	1.11228159918123	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: