YRC Public Data Repository - Protein Structure Prediction

Protein:	yam8
Organism:	Schizosaccharomyces pombe
Length:	486 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for yam8.

Description	E-value	Query Range	Subject Range
gi\|11280533 - gi\|11280533\|pir\|\|JC7212 stretch-activated Ca2+-permeable channel protein homolog, Yam8 - fission yea...	720.0	[0..1]	[486..1]
gi\|28949941 - gi\|28949941\|emb\|CAD70927.1\| related to MID1 protein [Neurospora crassa]	562.0	[0..33]	[481..160]
gi\|28922554, gi\|... - gi\|32413018\|ref\|XP_326989.1\| hypothetical protein [Neurospora crassa], gi\|28922554\|gb\|EAA31782.1\| hy... gi\|85100713 - gi\|85100713\|ref\|XP_961018.1\| hypothetical protein [Neurospora crassa OR74A]	544.0	[0..33]	[470..160]
gi\|42554592, gi\|... - gi\|46126081\|ref\|XP_387594.1\| hypothetical protein FG07418.1 [Gibberella zeae PH-1], gi\|42554592\|gb\|E...	534.0	[0..42]	[482..122]
gi\|45190410, gi\|... - gi\|45190410\|ref\|NP_984664.1\| AEL197Cp [Ashbya gossypii ATCC 10895], gi\|44983306\|gb\|AAS52488.1\| AEL19... gi\|44983306 - gi\|44983306\|gb\|AAS52488.1\| AEL197Cp [Ashbya gossypii ATCC 10895]	520.0	[0..28]	[462..44]
gi\|68490426, gi\|... - gi\|68490426\|ref\|XP_710963.1\| hypothetical protein CaO19.10724 [Candida albicans SC5314], gi\|46432228... orf19.10724 - MID1 CGDID:CAL0003216 Assembly 19, Contig19-20171 (11393, 9714) CDS, reverse complemented, translate...	513.0	[0..19]	[483..99]
gi\|39943980, gi\|... - gi\|39943980\|ref\|XP_361527.1\| hypothetical protein MG04001.4 [Magnaporthe grisea 70-15], gb\|EAA50242....	511.0	[0..37]	[461..397]
gi\|27447377, gi\|... - gi\|27447377\|gb\|AAM47512.1\| calcium channel MID1 [Aspergillus nidulans], gi\|27447361\|gb\|AAM47511.1\| c... gi\|49130549, gi\|... - gi\|67903710\|ref\|XP_682111.1\| hypothetical protein AN8842.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	481.0	[0..22]	[484..106]
gi\|151944256 - gi\|151944256\|gb\|EDN62535.1\| conserved protein [Saccharomyces cerevisiae YJM789] MID1_YEAST - Stretch-activated cation channel MID1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MI... gi\|207341958 - gi\|207341958\|gb\|EDZ69872.1\| YNL291Cp-like protein [Saccharomyces cerevisiae AWRI1631] MID1 - N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stre... gi\|190409259 - gi\|190409259\|gb\|EDV12524.1\| N-glycosylated integral plasma membrane protein [Saccharomyces cerevisia...	444.0	[0..69]	[459..95]

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Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFFFSTHLIL KILFFWSITR NIFGATYTSL LLNNTINGNI NDQSTAYYNL TWEGNTAYNV  60
   61 SLTLSTCTAF DGANDLMLYI SNNTFDEALP LDNFTITASE NGLATIFVTG YSPLYIAVSS 120
  121 AFSQFAPNFF VESGESTLEG NNVINYELAA GIDTPFSQYN ATKFLFAQDT DFQAALLITG 180
  181 NLTT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [185-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NETSIIPSYE IYVNPSNSTY DNTFNKFSSS FCAFQNNPST VNTNNADRSM TLRGLGPFAK  60
   61 EQFYLKGLDP NVTYTAYLVE PNIG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [269-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QPGGTVYPGV TFTTKTSPAC QLIYDLQFCS EVAYAVPGNS SLFSASALAE WYDQQAYGYY  60
   61 QNFTYTLDLI PCNATSWSAY SLLKNCSDCA NSYKNWLCAS VIPRCADIND NSSYLIYKNY 120
  121 DSRYPLIDEV IQPGPYKEVL PCSYLCYSLA SSCPLDLGFA CPKAGYGLEF SYGEVSNVTG 180
  181 LITCNAPGVE FYESGSALLN ISWRTFFISL IFWILFVE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.57
Match:	1ijxA
Description:	Secreted Frizzled-related protein 3 (SFRP-3;fzb)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transmembrane receptor activity	1.96928126941717	bayes_pls_golite062009
receptor activity	1.93198638186764	bayes_pls_golite062009
binding	1.7353571770087	bayes_pls_golite062009
signal transducer activity	1.71958201584504	bayes_pls_golite062009
molecular transducer activity	1.71958201584504	bayes_pls_golite062009
protein binding	1.03919942773652	bayes_pls_golite062009
Wnt receptor activity	0.129505171265921	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: