YRC Public Data Repository - Protein Structure Prediction

Protein:	dlc2
Organism:	Schizosaccharomyces pombe
Length:	85 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dlc2.

Description	E-value	Query Range	Subject Range
gi\|76642713 - gi\|76642713\|ref\|XP_593596.2\| PREDICTED: similar to dynein light chain-2 [Bos taurus]	174.0	[0..2]	[85..157]
gi\|50758408 - gi\|50758408\|ref\|XP_415908.1\| PREDICTED: similar to dynein light chain-2 [Gallus gallus]	174.0	[0..2]	[85..439]
gi\|112418924 - gi\|112418924\|gb\|AAI22095.1\| Dnl2 protein [Danio rerio]	158.0	[0..2]	[85..42]
gi\|73985240 - gi\|73985240\|ref\|XP_533775.2\| PREDICTED: similar to dynein, cytoplasmic, light peptide [Canis familia...	157.0	[0..5]	[85..87]
gi\|47168753, gi\|... - gi\|47168753\|pdb\|1RE6\|B Chain B, Localisation Of Dynein Light Chains 1 And 2 And Their Pro- Apoptotic...	157.0	[0..2]	[85..11]
gi\|72044059, gi\|... - gi\|72046933\|ref\|XP_785110.1\| PREDICTED: similar to dynein light chain-2 [Strongylocentrotus purpurat... DYL1_ANTCR - Dynein light chain LC6, flagellar outer arm OS=Anthocidaris crassispina PE=3 SV=1 DYL1_HELCR - Dynein light chain LC6, flagellar outer arm OS=Heliocidaris crassispina PE=3 SV=1	155.0	[0..2]	[85..6]

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Predicted Domain #1

Region A:
Residues: [1-85]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVIKAVDMS EKMQQEAIHA AVQAMEKFTI EKDIAAFIKR EFDKKFSPTW HCIVGRNFGS  60
   61 FVTHESRHFI YFYLGTVAFL LFKSG

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Detection Method:	PSI-BLAST
Confidence:	39.045757
Match:	1re6A
Description:	Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
microtubule motor activity	9.69298846835381	bayes_pls_golite062009
motor activity	5.85494716006373	bayes_pls_golite062009
dynein intermediate chain binding	4.30226487277718	bayes_pls_golite062009
nitric-oxide synthase regulator activity	3.06572632418145	bayes_pls_golite062009
dynein binding	2.90318309608701	bayes_pls_golite062009
cytoskeletal protein binding	2.8232927372914	bayes_pls_golite062009
binding	2.04793419379986	bayes_pls_golite062009
protein binding	1.75479345161448	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.47503021587966	bayes_pls_golite062009
pyrophosphatase activity	1.40860884968216	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.39154744890125	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.38919307572739	bayes_pls_golite062009
ATPase activity, coupled	1.20571334292956	bayes_pls_golite062009
ATPase activity	0.96367371812709	bayes_pls_golite062009
catalytic activity	0.448769452796145	bayes_pls_golite062009
hydrolase activity	0.442050017414837	bayes_pls_golite062009
protein dimerization activity	0.257276734446829	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: