YRC Public Data Repository - Protein Structure Prediction

Protein:	dbr1
Organism:	Schizosaccharomyces pombe
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for dbr1.

Description	E-value	Query Range	Subject Range
DBR1_SCHPO - Lariat debranching enzyme OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=dbr1 PE=3 SV=2 dbr1 - RNA lariat debranching enzyme Dbr1	626.0	[0..1]	[461..1]
gi\|42545849, gi\|... - gi\|46105348\|ref\|XP_380478.1\| hypothetical protein FG00302.1 [Gibberella zeae PH-1], gi\|42545849\|gb\|E...	532.0	[0..14]	[463..9]
gi\|6019470, gi\|7... - ref\|NP_057300.1\| debranching enzyme homolog 1 [Homo sapiens], gi\|6019470\|gb\|AAD53327.2\| RNA lariat ...	528.0	[0..16]	[415..1]
gi\|109049199 - gi\|109049199\|ref\|XP_001114637.1\| PREDICTED: similar to debranching enzyme homolog 1 isoform 2 [Macac...	520.0	[0..16]	[404..1]
gi\|73990217 - gi\|73990217\|ref\|XP_852077.1\| PREDICTED: similar to debranching enzyme homolog 1 isoform 2 [Canis fam...	516.0	[0..16]	[404..1]
gi\|13879368 - gi\|13879368\|gb\|AAH06661.1\| Dbr1 protein [Mus musculus]	513.0	[0..16]	[382..1]
DBR1_DANRE - Lariat debranching enzyme OS=Danio rerio GN=dbr1 PE=1 SV=1	513.0	[0..16]	[398..1]

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Predicted Domain #1

Region A:
Residues: [1-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYFARLKPP PAFLKMRVGV QGCCHGILDN LYILAEKRKV DLLIIGGDFQ ALRNVSDYHG  60
   61 ISMPPKFKRL GDFFNYYNGR NKAPILTIFV GGNHEASNYL DELPYGGWVA PNIYYMGRSS 120
  121 VINVGGLRIA GISGIYSAMD YKKGRYEGLP YNYKMLKSIY HTREFDVLSL KSLQKPIDIF 180
  181 LSHDWPRGIE QHGDVAKLLR HKPFFRNEVE RNDLGSPALE ELLVELKPRY WMAAHLHTKF 240
  241 TAVVHHNSQE DDGKLSCSSK DVTSSGFSMK GLNEPSQERL PVEKEQNDKS DEEGSNNEQE 300
  301 EKQDKKQSTN RDLCRKES

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.55
Match:	2yvtA
Description:	No description for 2yvtA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.30037658165549	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.03603874199452	bayes_pls_golite062009
binding	0.908738313033381	bayes_pls_golite062009
hydrolase activity	0.880072091351833	bayes_pls_golite062009
phosphoprotein phosphatase activity	0.768201004870964	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.634242884531037	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.463083693607652	bayes_pls_golite062009
phosphatase activity	0.325160962990544	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [319-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CKKEPSLSSS DQVTKFLALD KCLPRRSYFE VVEIEPVEIP DSGAPYMQYD SEWLSVLRAM  60
   61 HPFQSHTIEQ DPPLPSLEVV KTLKRKEEIW VDENLVKKDK LGIPRNFCQT APPHSRDITE 120
  121 NMQRKFSSMS MFLIPFSFFI YKPSDGCL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	100.026872
Match:	PF05011.4
Description:	No description for PF05011.4 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: