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View Structure Prediction Details

Protein: ctf1
Organism: Schizosaccharomyces pombe
Length: 363 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ctf1.

Description E-value Query
Range
Subject
Range
gi|76689281 - gi|76689281|ref|XP_881384.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
237.0 [0..5] [357..189]
gi|73976781 - gi|73976781|ref|XP_857374.1| PREDICTED: similar to Polyadenylate-binding protein 4 (Poly(A)-binding ...
231.0 [0..5] [357..189]
gi|41388837 - gi|41388837|gb|AAH65540.1| PABPC4 protein [Homo sapiens]
229.0 [0..5] [357..189]
gi|109002439 - gi|109002439|ref|XP_001113342.1| PREDICTED: poly A binding protein, cytoplasmic 4 [Macaca mulatta]
CCDS438.1_1 - null
229.0 [0..5] [357..189]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMTAGNVVF VGNIPYDVSE QQMTEIFNQV GPVKTFKLVL DPETGSGKGY GFCEFFDSET  60
   61 TAMAVRKLNN SELGPRKIRV EFPSNDPRR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.39794
Match: 1p1tA
Description: NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 5.15097136329571 bayes_pls_golite062009
mRNA binding 4.05281507540116 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
3.4479220904723 bayes_pls_golite062009
binding 3.05116833253954 bayes_pls_golite062009
single-stranded RNA binding 1.46469774223879 bayes_pls_golite062009
poly-pyrimidine tract binding 1.36691748240059 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
snRNA binding 0.73428616955527 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
protein binding 0.42571879933058 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQSYEYTERT DRYMEQQNAH ESSYNSRFIP PVLHSTSSLP ASQGGGMPSP AIYSSSMATN  60
   61 LNKNINSTSV PAYNFHNSMT SDFDSASQP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [179-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTDAYNARTF QYNKSSQNKG DYTSGTSISN PTSIPLAPSV VQVLSTFSAQ ELLNMLSKLQ  60
   61 TVVHIAPEEA RRLLIANPAL PYAAFQAMLL MNLVDANVLQ QVVVAVKNKN MHQPASATSS 120
  121 PPSVPQKIPS SNHKSQQANG SDQGNEGKRM ALIQQLLALT PEQINALPPA QRDQILSIRR 180
  181 QHFRQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle