YRC Public Data Repository - Protein Structure Prediction

Protein:	crb3
Organism:	Schizosaccharomyces pombe
Length:	446 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for crb3.

Description	E-value	Query Range	Subject Range
gi\|186464325, gi... - gi\|23128981\|ref\|ZP_00110817.1\| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi\|18668187...	441.0	[0..1]	[444..1178]
gi\|75701503, gi\|... - gi\|75907778\|ref\|YP_322074.1\| ribosome assembly protein 4 (RSA4) [Anabaena variabilis ATCC 29413], gi...	428.0	[0..1]	[444..1092]
gi\|35214926, gi\|... - gi\|37523920\|ref\|NP_927297.1\| WD repeat-containing protein [Gloeobacter violaceus PCC 7421], gi\|35214...	424.0	[0..2]	[444..656]
gi\|71675046, gi\|... - gi\|71675046\|ref\|ZP_00672792.1\| G-protein beta WD-40 repeat [Trichodesmium erythraeum IMS101], gi\|716...	417.0	[0..1]	[442..942]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=... gi\|25530855 - pir\|\|AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)	415.0	[0..1]	[444..954]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELLLSGCEA IEGEPSNVLC HNLHTGTLVS TFRQSSPAKN ATCTTLNHLL SAQHTRPQLN  60
   61 IHNFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.09691
Match:	1p22A
Description:	F-box/WD-repeat protein 1 (beta-TRCP1)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [66-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEILDQSIIL PEILICVQSS PCGSWLAAGT EKGNLYIWSL KSGALIYFFR AHYQPLTILK  60
   61 FSNDGMVLFT ASNDGDVFAW LISTLVDQNS TFETSNSSVK AISHFSGHKR SIVSMEIGPG 120
  121 PIVSGRLYTA SEDNTIRIWD VSTGNLLTTI ALPSTPSCMT VDPSERVVYV GNEKGIIWIP 180
  181 LYTGSSTFSN NVKEKKRVTS VDNTTIPNAI GGMGRVVDYN DSRESSIISC QSPITTLTVS 240
  241 FDASLLISGD KDGNVLVWDS VSRQVLRRLV QYYSPVSFLQ CKVDKISFYS NSSLSFPVLK 300
  301 RMITNEYLNS DVRICIQDDG VEQLMQPENI LKISSDIVTQ GSESSWRAKA ETSEMQLKEA 360
  361 KRLFYELKQI HQALWEKYLQ K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.0
Match:	1vyhC
Description:	PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.83286470399158	bayes_pls_golite062009
snoRNA binding	1.75441121456645	bayes_pls_golite062009
	1.56935945513861	bayes_pls_golite062009
RNA binding	1.50295916950465	bayes_pls_golite062009
transcription regulator activity	1.25687092973217	bayes_pls_golite062009
nucleic acid binding	1.20712373307552	bayes_pls_golite062009
protein binding	0.987581964031738	bayes_pls_golite062009
DNA binding	0.711274653406079	bayes_pls_golite062009
transcription factor activity	0.243992994917491	bayes_pls_golite062009
ligase activity	0.20682813699621	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: