YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC29A4.04c
Organism:	Schizosaccharomyces pombe
Length:	474 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC29A4.04c.

Description	E-value	Query Range	Subject Range
gi\|108708379, gi... - gi\|34896278\|ref\|NP_909483.1\| putative centromere/microtubule binding protein [Oryza sativa], gi\|2156...	547.0	[0..5]	[470..49]
DKC1_MOUSE - H/ACA ribonucleoprotein complex subunit 4 OS=Mus musculus GN=Dkc1 PE=1 SV=3	537.0	[0..1]	[444..27]
CBF5_ASPFU - Centromere/microtubule-binding protein cbf5 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / ... CBF5_ASPFU - Centromere/microtubule-binding protein cbf5 OS=Aspergillus fumigatus GN=cbf5 PE=2 SV=1 gi\|159126206 - gi\|159126206\|gb\|EDP51322.1\| pseudouridylate synthase family protein [Aspergillus fumigatus A1163]	533.0	[0..1]	[455..3]
DKC1_RAT - H/ACA ribonucleoprotein complex subunit 4 OS=Rattus norvegicus GN=Dkc1 PE=1 SV=4	530.0	[0..1]	[459..28]
gi\|109132884 - gi\|109132884\|ref\|XP_001090867.1\| PREDICTED: dyskerin [Macaca mulatta]	529.0	[0..1]	[445..110]
gi\|123998617, gi... - gi\|123998617\|gb\|ABM86910.1\| dyskeratosis congenita 1, dyskerin [synthetic construct], gi\|123984635\|g... gi\|14602859 - gi\|14602859\|gb\|AAH09928.1\| Dyskeratosis congenita 1, dyskerin [Homo sapiens]	521.0	[0..1]	[445..27]

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Predicted Domain #1

Region A:
Residues: [1-356]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDTHPGVDF MIKPEATSAS KIDTAEWPLL LKNFDKLLVR TGHYTPIPCG NNPLKRPIAE  60
   61 YVSSGVINLD KPANPSSHEV VAWVKKILRV EKTGHSGTLD PKVTGCLIIC NDRATRLVKS 120
  121 QQSAGKEYVC VLRLHDSVEG ERNVASAIET LTGALFQRPP LISAVKRQLR IRSIYESKLI 180
  181 EFDNERNLAV FWASCEAGTY MRTLCVHLGL LLGVGGHMQE LRRVRSGCLS ENDDIVTMHD 240
  241 VLDAQWIYDN TRDESYLRRV IRPLESLLVG YKRIVVKDSA VNAICYGAKL MIPGLLRYEA 300
  301 GIEVNEEIVL ITTKGEAIAV GIAQMSTVEL STCDHGVVAK VKRCIMERDV YPRRWG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	105.0
Match:	2hvyA
Description:	No description for 2hvyA was found.

Predicted functions:

Term	Confidence	Notes
pseudouridine synthase activity	5.60483019625575	bayes_pls_golite062009
intramolecular transferase activity	4.62815459483632	bayes_pls_golite062009
isomerase activity	3.43067391737824	bayes_pls_golite062009
catalytic activity	2.39224964671205	bayes_pls_golite062009
ligase activity	0.636073507077293	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [357-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGPQSMKKKT LKKEGKLDKY GRPNENTPAD WSKSYIDYSD PNAEVAKPAP VVAPAAPTVE  60
   61 AEVNGVEDSK KRKSVESSEK DEDEAAKKEE KRRKKEAKKE KKEKKEKKEK KEKKKKSE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.270	0.097	pseudouridylate synthase activity	d.93.1	SH2 domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: