YRC Public Data Repository - Protein Structure Prediction

Protein:	pap1
Organism:	Schizosaccharomyces pombe
Length:	552 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pap1.

Description	E-value	Query Range	Subject Range
gi\|101092, gi\|5001 - gi\|5001\|emb\|CAA40363.1\| AP-1-like transcription factor [Schizosaccharomyces pombe], pir\|\|S15664 tran...	384.0	[0..1]	[542..1]
gi\|4100263 - gi\|4100263\|gb\|AAD00802.1\| Cap1 [Candida albicans] gi\|46443503, gi\|... - gi\|68468526\|ref\|XP_721582.1\| hypothetical protein CaO19.9191 [Candida albicans SC5314], gi\|46443503\|...	242.0	[0..45]	[550..9]
AP1_KLULA - AP-1-like transcription factor OS=Kluyveromyces lactis GN=YAP1 PE=3 SV=1 AP1_KLULA - AP-1-like transcription factor OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NB...	222.0	[0..26]	[548..1]
gi\|85085674 - gi\|85085674\|ref\|XP_957544.1\| related to AP-1-like transcription factor [MIPS] [Neurospora crassa OR7... gi\|32405222, gi\|... - gi\|32405222\|ref\|XP_323224.1\| related to AP-1-like transcription factor [MIPS] [Neurospora crassa], g...	221.0	[0..22]	[551..84]
gi\|16945426 - gi\|16945426\|emb\|CAB91681.2\| related to AP-1-like transcription factor [Neurospora crassa] gi\|157071403, gi... - gi\|164426604\|ref\|XP_957544.2\| hypothetical protein NCU03905 [Neurospora crassa OR74A], gi\|157071403\|...	216.0	[0..22]	[551..84]
gi\|67901052, gi\|... - gi\|67901052\|ref\|XP_680782.1\| hypothetical protein AN7513.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	203.0	[0..43]	[550..121]
gi\|42549157, gi\|... - gi\|46129230\|ref\|XP_388976.1\| hypothetical protein FG08800.1 [Gibberella zeae PH-1], gi\|42549157\|gb\|E...	170.0	[0..4]	[551..93]
gi\|54657094 - gi\|54657094\|gb\|EAL35927.1\| DNA-directed RNA polymerase (EC 2.7.7.6) II largest chain [Cryptosporidiu... gi\|67597591 - gi\|67597591\|ref\|XP_666157.1\| DNA-directed RNA polymerase II largest chain [Cryptosporidium hominis T...	169.0	[0..197]	[411..1672]
gi\|46228363 - gi\|46228363\|gb\|EAK89262.1\| putative DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' ... gi\|66359288 - gi\|66359288\|ref\|XP_626822.1\| DNA-directed RNA polymerase,possible RNA polymerase A/beta'/A'' subunit...	169.0	[0..197]	[424..1679]

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Predicted Domain #1

Region A:
Residues: [1-162]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGQTETLSS TSNIPIAKAE PEQSADFSAS HKKRGPVSDR SSRRTSSEEV DLMPNVDDEV  60
   61 DGDVKPKKIG RKNSDQEPSS KRKAQNRAAQ RAFRKRKEDH LKALETQVVT LKELHSSTTL 120
  121 ENDQLRQKVR QLEEELRILK DGSFTFEMSL PHRNPSLSSL PT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.0
Match:	1gd2E
Description:	PAP1
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [163-356]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGFSSNFAHM KDGISPQSNL HLSPNSIEKP NMHQNVLHND RSADNLNHRY QVPPTLVDSN  60
   61 SAQGTLSPET PSSSDSPSNL YLNYPKRKSI THLHHDCSAL SNGENGEDVA DGKQFCQKLS 120
  121 TACGSIACSM LTKTTPHRAS VDILSNLHES TVSPPMADES VQRSSEVSKS IPNVELSLNV 180
  181 NQQFVSPFGG TDSF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [357-475]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLPTDTGLDS LFEPDSAIEN SHLKNVVMEP ELFQAWREPA ESLDKEFFND EGEIDDVFHN  60
   61 YFHNSNENGD LITNSLHGLD FLENANESFP EQMYPFIKHN KDYISNHPDE VPPDGLPQK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [476-552]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKHDTSSQMP SENEIVPAKE RAYLSCPKVW SKIINHPRFE SFDIDDLCSK LKNKAKCSSS  60
   61 GVLLDERDVE AALNQFN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.39794
Match:	1sseB
Description:	Solution structure of the oxidized form of the Yap1 redox domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits