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View Structure Prediction Details

Protein: DIP1-PB
Organism: Drosophila melanogaster
Length: 409 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIP1-PB.

Description E-value Query
Range
Subject
Range
gi|11558057, gi|... - gi|11558057|emb|CAC17711.1| chromatin component KLETT [Drosophila melanogaster], gi|11558046|emb|CAC...
280.0 [0..1] [409..1]

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Predicted Domain #1
Region A:
Residues: [1-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSVGQRVAF LSTHWTSPLQ NPNATVKPLI QMPLQAANVQ EQQSSPVALY PTSASPVAVQ  60
   61 SPQDAFLAVQ SPGAPAPVQL ANSSDQQNNP DADAIASKLP MPVIIKEEPI SVNDEPSVDN 120
  121 IEDNTSASTS ASGIGGKIPF KKIFQKRKKS SERTRDKKLR QNRQLRKSML PKNALMALNE 180
  181 VKGVTISDFT IDSNTDGGFT AVVTVNSNQY EGKGTSKMTA KNAACEKAWR DFIIAKM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1qu6A
Description: dsRNA-dependent protein kinase pkr
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.94193673826237 bayes_pls_golite062009
nucleic acid binding 1.04630961873875 bayes_pls_golite062009
RNA binding 0.41703783699663 bayes_pls_golite062009
protein binding 0.32114973384806 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [238-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPKPPRIHQV EMGSEPMDIN EDEADAPDDD LPMLNLASFA IYKLFAEWER EGYVVPEMHP  60
   61 SANAAQQAGG DAGTPVPPVP KEPKKPPVRT ELPSGWETMH PATILCIMRP GLNYVDYGSS 120
  121 GDKTNGMQHL GIMVDNQEFH ANGRSKKIAR RNVAVKVCNS LFGTNFTYSD TT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 1o0wA
Description: RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.94193673826237 bayes_pls_golite062009
nucleic acid binding 1.04630961873875 bayes_pls_golite062009
ribonuclease activity 0.868825189258668 bayes_pls_golite062009
nuclease activity 0.810795014450932 bayes_pls_golite062009
endonuclease activity 0.808265327042919 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.580369692270212 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.540638671994607 bayes_pls_golite062009
RNA binding 0.41703783699663 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.323139941667645 bayes_pls_golite062009
protein binding 0.32114973384806 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle