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View Structure Prediction Details

Protein: FBpp0298023, Pfr...
Organism: Drosophila melanogaster
Length: 536 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0298023, Pfr....

Description E-value Query
Range		 Subject
Range
Pfrx-PB, Pfrx-PG - The gene 6-phosphofructo-2-kinase is referred to in FlyBase by the symbol Dmel\Pfrx (CG3400, FBgn002...
gi|220946630 - gi|220946630|gb|ACL85858.1| Pfrx-PA [synthetic construct]
 569.0 [0..1] [536..181]

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Predicted Domain #1
Region A:
Residues: [1-536] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDMPYNTSPS LRVRTTSLNQ LKKTADLAIE NELHVCPSVM SEELRKLLPP TSETVMTKPF  60
   61 PIRGERTIAD CTTPHVIAMV GLPARGKTFI SKKLARYLNW IGISTRVFNL GEYRRHATTA 120
  121 YKSHEFFRAD NEEAMAIRNR CANQALHDSC DWLLSGQGSI AVFDATNSTR DRRQLIHDIV 180
  181 VKQHGFRLFF VESICDDPQI IEQNILEVKV SSPDYLNMNT ELVVRDFLQR IEHYEERYQP 240
  241 IDEVTESHLS FMKVYNAGKK VVVYNNEGHV ESRIVYYLMN IHITPRTIYL TRHGESEYNL 300
  301 SGLIGGDSNL SARGHQYANA LSTFIAQQQI DGLRVWTSWM KRAIQTVADV KAPQERWKAL 360
  361 NEIDAGHCEE MTYEQIKEKF PEEFKARDVN KFAYRYPRGE SYEDLVARLE PVIMELERQG 420
  421 NVLVVSHQAV LRCLFAYFLD KSADELPYLY VPLHTVIKLT PVAYGCKVEH IKLPIDAVDT 480
  481 HRPKPKIPGD VSEPGLDGLS GELVAPDGVG KVLIVGDDVA TATNGNGGRV DVQAHQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 1bifA
Description: 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE BIFUNCTIONAL ENZYME COMPLEXED WITH ATP-G-S AND PHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
6-phosphofructo-2-kinase activity 5.42792629395033 bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity 5.3758259177501 bayes_pls_golite062009
phosphofructokinase activity 4.74681837647377 bayes_pls_golite062009
phosphoglycerate mutase activity 3.38777226675734 bayes_pls_golite062009
fructose binding 2.65431677206223 bayes_pls_golite062009
fructose-6-phosphate binding 2.61827203165744 bayes_pls_golite062009
phosphatase activity 2.20711859657073 bayes_pls_golite062009
phosphoric ester hydrolase activity 2.0220580269993 bayes_pls_golite062009
carbohydrate kinase activity 1.86382423322759 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.78167518994202 bayes_pls_golite062009
kinase activity 1.67050219347378 bayes_pls_golite062009
carbohydrate phosphatase activity 1.56016941506609 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.3848751235482 bayes_pls_golite062009
catalytic activity 1.37714494241232 bayes_pls_golite062009
hydrolase activity 1.32674664996211 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.24295845488314 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.08151102259045 bayes_pls_golite062009
nucleic acid binding 0.974702705020209 bayes_pls_golite062009
intramolecular transferase activity, phosphotransferases 0.916759493094631 bayes_pls_golite062009
structural constituent of ribosome 0.867181425037322 bayes_pls_golite062009
binding 0.864238150099353 bayes_pls_golite062009
transferase activity 0.709223678750312 bayes_pls_golite062009
DNA-dependent ATPase activity 0.70364355116614 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.688993364310212 bayes_pls_golite062009
guanyl nucleotide binding 0.656009904481476 bayes_pls_golite062009
guanyl ribonucleotide binding 0.64416740142962 bayes_pls_golite062009
GTP binding 0.643084645864898 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.561773791863863 bayes_pls_golite062009
DNA binding 0.522586598136164 bayes_pls_golite062009
GTPase activity 0.406399103964327 bayes_pls_golite062009
isomerase activity 0.275500708652009 bayes_pls_golite062009
transcription regulator activity 0.261132792329283 bayes_pls_golite062009
protein binding 0.236742803345453 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.141310691160109 bayes_pls_golite062009
ion transmembrane transporter activity 0.0935614991493088 bayes_pls_golite062009
protein kinase activity 0.0646123847220056 bayes_pls_golite062009
cation transmembrane transporter activity 0.0137537621821964 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
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