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View Structure Prediction Details

Protein: Aats-his-PB
Organism: Drosophila melanogaster
Length: 563 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Aats-his-PB.

Description E-value Query
Range
Subject
Range
gi|220960228, gi... - gi|220960228|gb|ACL92650.1| Aats-his-PA [synthetic construct], gi|220959048|gb|ACL92067.1| Aats-his-...
Aats-his-PA - The gene Histidyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-his (CG6335, FBg...
369.0 [0..1] [563..1]

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Predicted Domain #1
Region A:
Residues: [1-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTREQILE QIKVQGDLVR QLKAAKESKE KHLSNPHHVH VPSLKSFPAS PLQIDEEVAR  60
   61 LLALKATLGG DAAPTNQKFT LKTPKGTRDY GPQQMTLRQG VLDKIVQVFK RHGGEAIDTP 120
  121 VFELKVSSPG SHWSGMILFK TMRIEVLTGK YGEDSKLIYD LKDQGGEILS MRYDLTVPLA 180
  181 RYLAMNKISS IKRYHIAKVY RRDNPAMTKG RYREFYQCDF DIAGTYDPML PDAECVKIVS 240
  241 EILDTLDIGD YVIKLNHRQL LDGMFQACGV PADSFRTICS AVDKLDKSPW ADVRKEMVDE 300
  301 KGLDEAAADR IGEYVRLSGG AELVEQLLAN EKLKAVPNAV KGLEGMKQLL KYCSIFGLDK 360
  361 RVSFDLSLAR GLDYYTGVIY EGVLKGESAT VASPAKTSQQ NGEQANEPAT VGSVAGGGRY 420
  421 DNLVGMFDPR GKAVPCVGVS IGVERIFSVL EARAAASGLK LRTSDVEVYV ASAHKGLHEQ 480
  481 RLKVLNLLWD AGVKAEHSYK LNPKLLVQLQ HCEEHQIPLV VVLGDAELAQ GLVKLREVTT 540
  541 REETNVKLED LAAEIRRRQQ ASA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.0
Match: 1qf6A
Description: Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ligase activity, forming aminoacyl-tRNA and related compounds 7.89468709683036 bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds 7.89468709683036 bayes_pls_golite062009
aminoacyl-tRNA ligase activity 7.88410036819636 bayes_pls_golite062009
ligase activity 6.92073480193262 bayes_pls_golite062009
histidine-tRNA ligase activity 5.91343220471745 bayes_pls_golite062009
phenylalanine-tRNA ligase activity 2.99105702052936 bayes_pls_golite062009
serine-tRNA ligase activity 2.46505535069103 bayes_pls_golite062009
glycine-tRNA ligase activity 2.29229136935761 bayes_pls_golite062009
threonine-tRNA ligase activity 2.18642354927 bayes_pls_golite062009
catalytic activity 1.99372273395202 bayes_pls_golite062009
alanine-tRNA ligase activity 1.82594054955281 bayes_pls_golite062009
lysine-tRNA ligase activity 1.72324031407565 bayes_pls_golite062009
asparagine-tRNA ligase activity 0.921492123574877 bayes_pls_golite062009
binding 0.916222310895772 bayes_pls_golite062009
transcription regulator activity 0.375542987753806 bayes_pls_golite062009
nucleic acid binding 0.281662799812287 bayes_pls_golite062009
DNA binding 0.0309732052586011 bayes_pls_golite062009
aspartate-tRNA ligase activity 0.00572514744734753 bayes_pls_golite062009

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