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View Structure Prediction Details

Protein: Arp8-PA
Organism: Drosophila melanogaster
Length: 607 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Arp8-PA.

Description E-value Query
Range
Subject
Range
ACT2_SCHMA - Actin-2 OS=Schistosoma mansoni PE=2 SV=1
gi|6979994, gi|1... - gi|6979994|gb|AAF34686.1| actin [Schistosoma japonicum], gi|189503078|gb|ACE06920.1| unknown [Schist...
gi|186462275 - gi|186462275|gb|ACC78609.1| actin [Schistosoma bovis]
515.0 [0..102] [500..1]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRSRASSTS SGRHPAPPPI GLPQPQAQPL EAPKIIVIHP GSQHLRIGRA ADLNPLTLLH  60
   61 AVAYRRRPGA SDRPHHDPLL PPLDNVNSNS GLMVEFEEQR LVVSRILQHC VVDNKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLRVATPPQQ LAHFNRSSQA EKVPAPSGQM ADEPWLDREA PVLFDDRILR LGAVDARNYD  60
   61 IHFPIQRGEL NVHNEKGGSL QASMQHLERI WSYALEERLK IPLRKLGTHC AVLVVNDVYV 120
  121 RRHLREFVTL LLRRLGFRRC FLVQDSVAST FGAGIGYGCV VDIGAQKTSI ACIEDGISQL 180
  181 DARVRLSYGG GDLDQVLLLL LRKCGFPYRE CNVQESYVDA HLLDELKEKF CHLNASVCGA 240
  241 QEKHFNLRKH NGQWLRYTIQ VGDEALMAPL ALFHTELLNI TGRTKAVFTQ QAVQDQYDCE 300
  301 DCFDAEYLKE TGRKNGVRGG DILQLSTSAG YQPRPQLPVT ADDEELIVVD QDETISNCQS 360
  361 QLGAQTAGGQ MNSNGCYHNG QGLVLPLDQA II

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 145.0
Match: 2oanA
Description: No description for 2oanA was found.

Predicted functions:

Term Confidence Notes
structural constituent of cytoskeleton 3.14961582364442 bayes_pls_golite062009
cytoskeletal protein binding 3.11425505645918 bayes_pls_golite062009
actin binding 2.955791490673 bayes_pls_golite062009
binding 2.11855816699924 bayes_pls_golite062009
transcription regulator activity 2.09111975841662 bayes_pls_golite062009
DNA helicase activity 1.95284371697518 bayes_pls_golite062009
DNA binding 1.70014394990425 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.59975673209166 bayes_pls_golite062009
histone acetyltransferase activity 1.59975673209166 bayes_pls_golite062009
nucleic acid binding 1.53796369834496 bayes_pls_golite062009
actin filament binding 1.46443668299938 bayes_pls_golite062009
myosin binding 1.13621903736628 bayes_pls_golite062009
transcription factor activity 1.06678984888387 bayes_pls_golite062009
structural molecule activity 0.998075030492697 bayes_pls_golite062009
protein binding 0.956664772028256 bayes_pls_golite062009
kinase activity 0.650790710321692 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.575595567012379 bayes_pls_golite062009
nucleosome binding 0.329990231856661 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.324655711623803 bayes_pls_golite062009
catalytic activity 0.296484721581333 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.236498546608508 bayes_pls_golite062009
carbohydrate kinase activity 0.123282448317819 bayes_pls_golite062009
transferase activity 0.105619024604158 bayes_pls_golite062009
N-acetyltransferase activity 0.0571907728331915 bayes_pls_golite062009
transcription activator activity 0.0275592755061818 bayes_pls_golite062009
5'-3' DNA helicase activity 0.0183211661451317 bayes_pls_golite062009
ATP-dependent 5'-3' DNA helicase activity 0.0183211661451317 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [509-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSINRLSSYE TKRKMFGSIL LVGSSAKLPG LAAWLEQRIS QQVQSEVNVL IKGMDAGMVA  60
   61 WKGAAIMSVL ESARELWISQ NDWQRHGLRV LRERSPFLW

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.67
Match: 1k8kA
Description: Actin-related protein 3, Arp3
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle