| Protein: | mei-41-PA |
| Organism: | Drosophila melanogaster |
| Length: | 2517 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mei-41-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
1834.0 | [0..164] | [2517..1] |
|
Region A: Residues: [1-229] |
1 11 21 31 41 51
| | | | | |
1 MSTQRKDMWK LLYNHVNRNV SNFSGVYSVI EDILCQEPSL ISCSLVRELH NKFQDTFLLW 60
61 LLNKLAKCLS ESPDSSECIN LQRKILSSCC SNHPKLFERL VLAYVEAIEE THLQLSSLDL 120
121 GQLSNERKPA ITVRIFRCDV ECLQEFDPHC AIEDIKVPLE QADMYAKSLL EVLQHAHHIG 180
181 YATHGDIFSG SLHQALLILK ECDMDTKLAS LNYCHNVLRS QSASSWITN
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [230-442] |
1 11 21 31 41 51
| | | | | |
1 PDVGHYAQLT LEATAIMWSA VAKWLDMGCM TRQELKRLNI TTKLLLEVLH MRARPAHHLG 60
61 YLLLNEILSL PTAIELDDGL LETLSSYIQG QLEHSVVPLE QLVHLQQLML SHWHCHPTHL 120
121 VPILALMGLK QTEMRSGVVQ VLTQSLVEIL KKEEVLSKDW QKLIAILRGF KQLEKLILSQ 180
181 SQHKIAEHEG HIDSSVLAML PLQCEIIKVA DTN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [443-626] |
1 11 21 31 41 51
| | | | | |
1 WNNLSMQLVE LESKCSADRR HIHLEICSLL MQITFIRHFL KTQTQHQLLA ILQRHLKLSY 60
61 LCAIRLETPS SVHTQMQSFY AQQYMRLFQS EETQEIFCSN LPQLYISGFI KPEQLMKALP 120
121 TINNRSGRAQ VIRLLLCSQP GKLSVFKVKD RIELYCPKCR PLPKKLPGIY LGKCKQQLPC 180
181 PDFS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [627-1301] |
1 11 21 31 41 51
| | | | | |
1 STNLEMIAND LLFYPDFECI AQHLDLLCFE PNVILGLLRE TEALQKVSVK VIGQLVSAMR 60
61 VRSPEFLEQL ANLVLAAIKA MLAKPLTEQN VLQQRSMLNV LTAIAHMEDN EIWLFHWFKM 120
121 TFFFLVHTRS LVAQEAVLAA TEMCASQGLQ TIHLWNWYKR DALDLTVRLA LNVYLLDGVR 180
181 FTRSLRALTK MLGFTCVQEF TCKYHRLLTA MVLPHCIVNP LCKGVLVLIA KQMQKHIGTL 240
241 FSISFLRIYT HVFLTEEPEL ANSCIELVVS CTQSSLQQLM NADVKQTVAE LLIYFNRNPT 300
301 FVMRSFQSLL QLSIGSLEEL SSQTANAEFA NFIAERFLGV ITYFESCLSE PSFEKPLKEE 360
361 TLYSLGQIMR FVGSQHVTQF RFKIIAMLSF VHTLQEPRLQ RICLKIWHIF LHVVNVQELG 420
421 PSLGRIVATL QPLLADNESV KQVNDLYEFI ILRNASMLGT FITDLYFLDR MENVSPSIQK 480
481 CIRRHTAHLD LKGLAEEENQ SPPLVDQLRF LQKHITDECL QVRVYALQHL GDLFGRRRPK 540
541 LNSTILSELP LEPMLEQIVN VLMAGCQHDD SQLQMASAKC LGELGAIDAS YLPSNYNFAS 600
601 PQHLPLNILS DDFAVLALTS LCRGYQFQQN TKHVDSFSLA IQETLAICGI SPKEQKKVQL 660
661 WQSLPARMRQ LMEPM
|
| Detection Method: | |
| Confidence: | 9.0 |
| Match: | 1u6gC |
| Description: | Crystal Structure of The Cand1-Cul1-Roc1 Complex |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 1.72717267135753 | bayes_pls_golite062009 |
| protein binding | 1.01840651819417 | bayes_pls_golite062009 |
| kinase activity | 0.0760276596533398 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.0674767831653993 | bayes_pls_golite062009 |
| transferase activity | 0.0525163357236478 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.025201457801308 | bayes_pls_golite062009 |
| catalytic activity | 0.0114279309788371 | bayes_pls_golite062009 |
|
Region A: Residues: [1302-1440] |
1 11 21 31 41 51
| | | | | |
1 LHSCYTCVHR PSTCLQQPLF GSHYSHNYYE EWAFLWASRL IDYLPSSGRR HLLSSYKPCI 60
61 KRDSNMLSTF YPYILLHALL ECTTEQRNHI QEEFMAVLQA NEESSSSVRG RQELGAIKEN 120
121 AFKQFESRKY AAGIKPLAS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1441-1821] |
1 11 21 31 41 51
| | | | | |
1 TLVSDRKEDS SRVPRLAGKL CAELLDFLQR WLREWQRIHG RSTGGKPPET IDSNYRKIHE 60
61 FLNLIPKLLV SRASYNCGEY ARALSYLESY LEEGEDKSQR LLEQFTFLVE VYGSLRDPDS 120
121 VEGAVQVRSY DMSVTQDILV NRLVERQQDM ITSYEQLLSS TDQMQPDHVR AMIDAYLRDT 180
181 PKTAQLIADG LWQRLSDRYS DQCFAECKSE LLWRLGSYDE MEELQSNWPA QCSQGCLKLR 240
241 RPLTTRIEFD SLLDGMRESV LEELRSCSAV QQHSYANAYD AVLKLHLVHE LHCSQELVEK 300
301 LEQDRDEDNQ EKLMKNYFDD WQYRLQIVQP QVRIQESIYS FRRNILAELQ RRLTDRNHLL 360
361 PHLKTELARI WLNSAQINRN A
|
| Detection Method: | |
| Confidence: | 15.09691 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1822-1886] |
1 11 21 31 41 51
| | | | | |
1 GQLQRAQLYI LKAAEYQPSG LFIERAKLLW QKGDQVMAMN YLEEQLSIMR SGCQGNVKQL 60
61 AAEQR
|
| Detection Method: | |
| Confidence: | 6.221849 |
| Match: | 2tmaA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1887-2517] |
1 11 21 31 41 51
| | | | | |
1 HLFFRGKYLQ AVYSAESMHL CADAVLKYFQ EAIAVHRQSE SCHVQMAQFL EKILEARQGG 60
61 KSEPTGEQDD MLINVMVNYA KSLRYGSEHV YQSMPRLISL WLDTTESSTN TEQVKKMNDL 120
121 LTNCCTALPT AVFYTVYSQM LSRLCHPVND VFTVLRNVII KLVEAYPQQS LWMLLPHFKS 180
181 AKAHRIKRCK LVLTDSRLQN STFQKLLQDF NSLTERLMDL TNKEVTLDRT YKLSDLDTRL 240
241 SKLCKQPEFS QILLPFEKYM QPTLPLNSDS NSSEGSHLPA NQSTVNWFPY QQIYISGFQE 300
301 SVLILRSAAK PKKLTIRCSD GKDYDVLVKP KDDLRRDARL MEFNGLVKRY LHQDAPARQR 360
361 RLHIRTYAVL PFNEECGLVE WLPNLASYRS ICMNLYAQRR LVMSTRQLQS LAVPLHESIE 420
421 RKREVFTKQL VPAHPPVFQE WLRQRFATPH SWYEARNTYI RTVAVMSMVG YILGLGDRHG 480
481 ENILFAEGNG DAVHVDFNCL FNQGELLPYP EVVPFRLTHN MIVAMGPLGV EGSFRKCCEI 540
541 TLRLLKQESK TLMSILRPFV YDVGAQTRKG AATAKITKDV QRIADRLQGH VKRQQANSIP 600
601 LSTEGQVNFL INEATKVDNL ASMYIGWGAF L
|
| Detection Method: | |
| Confidence: | 69.39794 |
| Match: | 1he8A |
| Description: | Phoshoinositide 3-kinase (PI3K) helical domain; Phoshoinositide 3-kinase (PI3K); Phoshoinositide 3-kinase (PI3K), catalytic domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 4.02689842795549 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 3.90280755052039 | bayes_pls_golite062009 |
| kinase activity | 3.79479290566599 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 3.52418803498373 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 3.25689179819529 | bayes_pls_golite062009 |
| transferase activity | 2.77204178459065 | bayes_pls_golite062009 |
| catalytic activity | 1.58699080719302 | bayes_pls_golite062009 |
| binding | 1.4090115174802 | bayes_pls_golite062009 |
| ATP binding | 1.17595199896949 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.14937361489985 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.12019766280871 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.92069223793838 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.91856284481973 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.89187631975697 | bayes_pls_golite062009 |
| nucleotide binding | 0.88568566446713 | bayes_pls_golite062009 |
| molecular transducer activity | 0.64449050025422 | bayes_pls_golite062009 |
| signal transducer activity | 0.64449050025422 | bayes_pls_golite062009 |
| protein binding | 0.507179243841744 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 0.39548279667137 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 0.33236349563013 | bayes_pls_golite062009 |
| receptor signaling protein activity | 0.2696429722379 | bayes_pls_golite062009 |
| phospholipid binding | 0.11116435936349 | bayes_pls_golite062009 |
