| Protein: | vap-PD, vap-PA, ... |
| Organism: | Drosophila melanogaster |
| Length: | 954 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for vap-PD, vap-PA, ....
| Description | E-value | Query Range |
Subject Range |
|
|
609.0 | [0..1] | [954..1] |
|
Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MADLIHLGNI DVVIQKDKPG SPTGCSDDGN LAGLGGMTGL GGIMAPGGID LGDLAQELDH 60
61 DEFDGPHMLN GERPAII
|
| Detection Method: |  |
| Confidence: | 60.522879 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
|
Region A: Residues: [78-651] |
1 11 21 31 41 51
| | | | | |
1 APPESEWYHG RLDRYSAESR LRGSSKLGSY LVRESDRKPG SYVLSYYGRT GINHFRITAV 60
61 CGDFYIGGRQ FISLSDLVGY YTSCSDLLKR ERLAIPVAPP EPVNDKKRVV AILPYTKMPE 120
121 TDELSFQKGD IFFVHNDMGD GWLWVTAHRT GEQGMIFREL VDDLDVSIDP NTVFPWFHPN 180
181 CTKNEAVDML VKAGPGSFLV RPSDNSPGDY SLFFHINNQI QRFRIEKKGV RYLMGGRTFE 240
241 CLDAVINRYR KEQIVEGHSL NHPVVNGIQP EFNQQYVVEK AAEKIYATLR ECRDQIGLKK 300
301 IKGIKHHGHL NKKSDKTTKW KQLYFALIND GSETQLCFYD NPKKTKPKGL IDLSCAYLYQ 360
361 CHDSLWERPY CFQIVERALP CLATVTYLCA PSQESYVEWI NSLKAQCDSQ LSRAQKKVSR 420
421 LRELRCLNLH VLEAHRLPFK LVPHPYCSIS LNQVKVGKTR VKIAPEPVWE EEFVLDDVPP 480
481 DVVSLTITLI SRGKRGKDSE VAELTIDLSS LKNGQETEGW YQLTGMTPMG EWGSLRLRMR 540
541 YLDDLIMPCE EYSPLQQLLL ESELYAVKAL AELC
|
| Detection Method: | |
| Confidence: | 22.522879 |
| Match: | 2b3oA |
| Description: | Crystal structure of human tyrosine phosphatase SHP-1 |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [652-954] |
1 11 21 31 41 51
| | | | | |
1 HNDRVPLATA LLRVFRQEKR ETELIRMLCQ AEVTRENETT TLFRGASLAT TLMDLYMRTE 60
61 CSGFLQSAVS ETVQRILESK QSAELNPTKM DVNDDACTNA EFLLQILDLV TQSIFTSPDA 120
121 CPRNVRFICS CLQKAVMAKW PTERLVRTRV VSGFIFLRLL CPALLNPRQF GLVSETPPMA 180
181 ATRSLVMVAK CLQNLANLIE FGGKEQYMEV VNPFILKNKE RMIVFLDQLS SVNDPNQPLG 240
241 MFVEQSTNLN SQDTGRELAT LHHICVSHSQ ELHELSNILS IKKLVTVTDM LTKHKLKYRE 300
301 MIS
|
| Detection Method: | |
| Confidence: | 85.30103 |
| Match: | 1werA |
| Description: | RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| GTPase regulator activity | 3.92341792218401 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 3.90121360274392 | bayes_pls_golite062009 |
| small GTPase regulator activity | 3.62030771158759 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 3.57820175827805 | bayes_pls_golite062009 |
| enzyme regulator activity | 3.46826704310039 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 3.36729905538951 | bayes_pls_golite062009 |
| GTPase activator activity | 3.18597454327808 | bayes_pls_golite062009 |
| enzyme activator activity | 2.92839426561878 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.61125915250884 | bayes_pls_golite062009 |
| actin binding | 2.416122069016 | bayes_pls_golite062009 |
| Rac GTPase activator activity | 2.11791567976149 | bayes_pls_golite062009 |
| binding | 1.62780792681766 | bayes_pls_golite062009 |
| microfilament motor activity | 1.44575799226586 | bayes_pls_golite062009 |
| molecular transducer activity | 1.42814294153578 | bayes_pls_golite062009 |
| signal transducer activity | 1.42814294153578 | bayes_pls_golite062009 |
| actin filament binding | 1.3598230579803 | bayes_pls_golite062009 |
| nucleic acid binding | 1.26917632007176 | bayes_pls_golite062009 |
| protein binding | 1.21496582666968 | bayes_pls_golite062009 |
| transcription regulator activity | 1.01803522412345 | bayes_pls_golite062009 |
| DNA binding | 0.813358382068686 | bayes_pls_golite062009 |
| receptor activity | 0.434186339265983 | bayes_pls_golite062009 |
| actin-dependent ATPase activity | 0.09145723094381 | bayes_pls_golite062009 |
