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View Structure Prediction Details

Protein: CG8939-PA
Organism: Drosophila melanogaster
Length: 817 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8939-PA.

Description E-value Query
Range		 Subject
Range
gi|109116848, gi... - gi|109116850|ref|XP_001116419.1| PREDICTED: similar to FtsJ homolog 3 isoform 3 [Macaca mulatta], gi...
 400.0 [0..1] [797..1]

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Predicted Domain #1
Region A:
Residues: [1-205] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKTKVGKT RKDKFYQLAK ETGLRSRAAF KLIQLNRKFG FLQQSQVCLD LCAAPGGWMQ  60
   61 VAKQNMPVSS IVIGVDLFPI RPIAGCIGLV EDITTEKCRQ SLTKELQSWK ADVVLHDGAP 120
  121 NVGRNWLYDA YQQICLTLNA LKLSTQFLRN GGWFVTKVFR SKDYNALLWV LKQLFKKVHA 180
  181 TKPSASRKES AEIFVVCQGY LAPDH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.0
Match: 1eizA
Description: RNA methyltransferase FtsJ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
rRNA methyltransferase activity 4.09362182773099 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein methyltransferase activity 3.92746815303714 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
histone methyltransferase activity 2.99461585647365 bayes_pls_golite062009
DNA-methyltransferase activity 2.43145108778901 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
transferase activity 2.22303238506686 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.04296107639729 bayes_pls_golite062009
rRNA (guanine) methyltransferase activity 2.00108769169811 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 1.83964463328968 bayes_pls_golite062009
tRNA methyltransferase activity 1.76571145896453 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.75675289134467 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.66871163498737 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 1.1103522853299 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
rRNA (uridine-2'-O-)-methyltransferase activity 0.90544396691236 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.89325812193225 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
rRNA (uridine) methyltransferase activity 0.742142092552002 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 0.672282175551951 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 0.672282175551951 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
binding 0.383237930789959 bayes_pls_golite062009
O-methyltransferase activity 0.250946859465502 bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity 0.234572322347698 bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity 0.0803947886180681 bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity 0.0803947886180681 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [206-681] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDPRLLDSKY VFEELDLDAK KKSSLLHPEK QKRIKAEGYT AQDIALRNDL AATEFLKAEN  60
   61 ALAALQGIGS IRIDDQRIAN HKKTTPEILE CCKDLKVLGR KDIKGLVQWW KDVRELFVEK 120
  121 ETPLVVGNAA DEKPKPLTQA EIEDMEDAEL QTQIETIVEE EKKDLKRKRK KTLKTKAKLH 180
  181 EKMNLNMVIK GDDGPVEEME HEIFDLKNIR TSAELDELLD VQPDFAVDES QPEETKLPKY 240
  241 KYFDKDEGNI NDDLNYDDDN DEEQSEASDD EDQINDKQGL GLSDDDNDEG NAKGKNKRKK 300
  301 RSENPLIKSN DFRDKNTKRE QRVQLWYEKD VLQNIQSDDD EETYDLNNLA KEFKAKGVAV 360
  361 LGESTLTPDA NEEVVQGKKA KRRARHETAT KDSSSESSES EDDANEDSDG EQPAAGTNAK 420
  421 KVRLSENEMA LGALLTRSKK TRRDLIDAAW NRYAFNDENV PVWFKLDEDE HMTKPT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [682-817] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PVPKELTAEY QRKLQEVNVR PIKKVMEAKA RKHRRATKRL AKAKKMAEKI MENSDATNHE  60
   61 KSKQLKKVYK KAQEKKKEVT YVVAKKQTAA RRARRPAGVK GRYKVVDPRE KKDKRSMDAK 120
  121 KRREKGSKGR KGKGRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.39794
Match: 2dfsA
Description: No description for 2dfsA was found.
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