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View Structure Prediction Details

Protein: Fer3HCH-PA
Organism: Drosophila melanogaster
Length: 186 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Fer3HCH-PA.

Description E-value Query
Range
Subject
Range
gi|47125326 - gi|47125326|gb|AAH70494.1| FTH1 protein [Homo sapiens]
233.0 [0..2] [180..44]
gi|114637918 - gi|114637918|ref|XP_001140124.1| PREDICTED: similar to Ferritin heavy chain (Ferritin H subunit) (Pr...
233.0 [0..9] [180..109]
gi|83404987 - gi|83404987|gb|AAI11079.1| Fth1 protein [Rattus norvegicus]
232.0 [0..3] [180..40]
gi|46562303 - gi|46562303|gb|AAT01287.1| ferritin [Coturnix japonica]
219.0 [0..11] [180..3]

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Predicted Domain #1
Region A:
Residues: [1-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWCFRDIRR HMCMLVRQNF AKSCEKKLND QINMELKASH QYLAMAYHFD RSDISSPGMH  60
   61 RFFLKASVEE REHAEKIMTY MNKRGGLIIL SSVPQPLPCF ASTLDALKHA MKMELEVNKH 120
  121 LLDLHALAGK EADPNLCDFI EANFLQEQVD GQKILADYIS QLEKAQNQVG EFLFDKYMGS 180
  181 GMHPAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1fhaA
Description: SOLVING THE STRUCTURE OF HUMAN H FERRITIN BY GENETICALLY ENGINEERING INTERMOLECULAR CRYSTAL CONTACTS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ferric iron binding 5.55100638826026 bayes_pls_golite062009
iron ion binding 3.10225782829614 bayes_pls_golite062009
binding 1.95813969002966 bayes_pls_golite062009
transition metal ion binding 1.70242943635222 bayes_pls_golite062009
cation binding 1.66873432300081 bayes_pls_golite062009
metal ion binding 1.66873432300081 bayes_pls_golite062009
ion binding 1.66140448750278 bayes_pls_golite062009
ribonucleoside-diphosphate reductase activity 0.366005079572569 bayes_pls_golite062009
protein binding 0.30514049100341 bayes_pls_golite062009
oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.289628933165632 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle