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View Structure Prediction Details

Protein: CG17333-PA
Organism: Drosophila melanogaster
Length: 243 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG17333-PA.

Description E-value Query
Range
Subject
Range
gi|62089394 - gi|62089394|dbj|BAD93141.1| glucosamine-6-phosphate deaminase 2 variant [Homo sapiens]
263.0 [0..8] [241..36]
gi|114593868 - gi|114593868|ref|XP_001143245.1| PREDICTED: similar to glucosamine-6-phosphate deaminase 2 variant [...
263.0 [0..8] [241..124]
gi|73974968 - gi|73974968|ref|XP_858777.1| PREDICTED: similar to glucosamine-6-phosphate deaminase 2 isoform 3 [Ca...
259.0 [0..8] [241..1]
gi|50747027 - gi|50747027|ref|XP_420726.1| PREDICTED: similar to glucosamine-6-phosphate deaminase 2; glucosamine-...
259.0 [0..8] [241..1]
gi|148226212, gi... - gi|38014417|gb|AAH60459.1| MGC68566 protein [Xenopus laevis], gi|148226212|ref|NP_001083469.1| hypot...
259.0 [0..8] [241..1]
GNPI2_BOVIN - Glucosamine-6-phosphate isomerase 2 OS=Bos taurus GN=GNPDA2 PE=2 SV=1
259.0 [0..8] [241..1]
GNPI2_MOUSE - Glucosamine-6-phosphate isomerase 2 OS=Mus musculus GN=Gnpda2 PE=1 SV=1
257.0 [0..8] [241..1]

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Predicted Domain #1
Region A:
Residues: [1-243]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKKGALKV IPSASEEQLV QALGDLLQRC SQEALAKHDK FSVGLSGGSL VQLLTKALKS  60
   61 CNLKTAKWVF FFCDERYVRL DDSDSTYGAY RAEWLTQLPC IQESQFVRAD TSQPLDACAA 120
  121 DYEAKVKSQV DRFDLLLLGM GPDGHTCSLF PEQPATLQET KRLVIPIRNS PKPPPERITF 180
  181 TLPLINKARN VAFVVTGAAK ASVVKSVFVD LDKKFPAAWV NPTKGQLTLI VDAGAGKEIE 240
  241 TLK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 68.09691
Match: 1ne7A
Description: HUMAN GLUCOSAMINE-6-PHOSPHATE DEAMINASE ISOMERASE AT 1.75 A RESOLUTION COMPLEXED WITH N-ACETYL-GLUCOSAMINE-6-PHOSPHATE AND 2-DEOXY-2-AMINO-GLUCITOL-6-PHOSPHATE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribose-5-phosphate isomerase activity 2.78510459473943 bayes_pls_golite062009
nucleic acid binding 2.17718456512191 bayes_pls_golite062009
intramolecular oxidoreductase activity 2.15381323621148 bayes_pls_golite062009
6-phosphogluconolactonase activity 1.97756803122763 bayes_pls_golite062009
transcription regulator activity 1.9283980201455 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 1.65800801564277 bayes_pls_golite062009
DNA binding 1.55389679363348 bayes_pls_golite062009
binding 1.53908996868286 bayes_pls_golite062009
catalytic activity 1.31732715713197 bayes_pls_golite062009
translation initiation factor activity 1.26125370316069 bayes_pls_golite062009
translation regulator activity 1.21635586954394 bayes_pls_golite062009
translation factor activity, nucleic acid binding 1.09424756417577 bayes_pls_golite062009
transcription factor activity 0.995059566132783 bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity 0.111185777194415 bayes_pls_golite062009
isomerase activity 0.102415560220489 bayes_pls_golite062009
protein binding 0.0293610121675921 bayes_pls_golite062009

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