YRC Public Data Repository - Protein Structure Prediction

Protein:	CG6999-PA
Organism:	Drosophila melanogaster
Length:	233 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG6999-PA.

Description	E-value	Query Range	Subject Range
gi\|76633747 - gi\|76633747\|ref\|XP_881817.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	170.0	[0..3]	[193..133]
gi\|94368985 - gi\|94368985\|ref\|XP_986117.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	169.0	[0..4]	[193..134]
gi\|114682135 - gi\|114682135\|ref\|XP_514668.2\| PREDICTED: poly(A)-binding protein, cytoplasmic 1-like [Pan troglodyte...	168.0	[0..3]	[193..133]
gi\|109091847 - gi\|109091847\|ref\|XP_001109542.1\| PREDICTED: poly(A) binding protein, cytoplasmic 1 [Macaca mulatta]	168.0	[0..3]	[193..133]
PABPC1L - poly(A) binding protein, cytoplasmic 1-like	168.0	[0..3]	[193..133]

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Predicted Domain #1

Region A:
Residues: [1-59]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVEETKLDE ARWGKPQTKE GESANGIANP SNDDKKELAN FKATFNSWAP EKKREKMHK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.0
Match:	1cvjA
Description:	Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [60-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGVILISNIP KDMDGDCLKE IMNLHSVVGR VYVQPETLSS FKTKKNMRKG WVEFISKSGA  60
   61 KKIALELNNK PITDGKSSRF RGLLWKMKFL PRFKWYYLTD RMDYELAVCK VRVWSQARKR 120
  121 ATFWYDPDQM EYFKKQVKKM KKMKKVKEAE MATRNAEMAA KKAEMAAKKL KKSA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	1fnxH
Description:	Hu antigen C (Huc)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	5.15097136329571	bayes_pls_golite062009
nucleic acid binding	4.92126426323641	bayes_pls_golite062009
mRNA binding	4.05281507540116	bayes_pls_golite062009
binding	3.64400841800969	bayes_pls_golite062009
	2.83802439076672	bayes_pls_golite062009
transcription regulator activity	1.92450390013691	bayes_pls_golite062009
DNA binding	1.8021593476478	bayes_pls_golite062009
poly-pyrimidine tract binding	1.69629099229571	bayes_pls_golite062009
single-stranded RNA binding	1.46469774223879	bayes_pls_golite062009
transcription factor activity	1.15127506309683	bayes_pls_golite062009
protein binding	1.12215421354121	bayes_pls_golite062009
mRNA 3'-UTR binding	0.591700155096213	bayes_pls_golite062009
sequence-specific DNA binding	0.383589644462932	bayes_pls_golite062009
snRNA binding	0.249682711188639	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: