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View Structure Prediction Details

Protein: CG3033-PA
Organism: Drosophila melanogaster
Length: 674 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG3033-PA.

Description E-value Query
Range
Subject
Range
gi|125983108, gi... - gi|54643633|gb|EAL32376.1| GA15765 [Drosophila pseudoobscura pseudoobscura], gi|125983108|ref|XP_001...
gi|125983108|ref... - GA15765-PA [Drosophila pseudoobscura], GA15765 [Drosophila pseudoobscura pseudoobscura]
739.0 [0..1] [674..1]

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Predicted Domain #1
Region A:
Residues: [1-413]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLLSDPSIS TQSKLVDGLA RHVRKVCYAL YVAGVAWFFC LALPEFNHGT YLSENALSPG  60
   61 LVYPEIRIDA NRLAIQLLEE LQRERKDHLS TTPHAWIAAK MNEFGLETHT HNYTLRYPFG 120
  121 GGKEYHGKNI YGILRAPRIA STEGIVFAAP YRAASSVHTD ISASVPLLLA FADFARRKNY 180
  181 WAKDLIFLIT EQEQLGMQAW LEAYHDGDRE LDLSKAYLRP GNLPARAGSL QAALNIEVQD 240
  241 LEIDHVDVRI EGLNGKLPNL DMFNLVQRIM AREGIASGYK QAPRKKRRHS QSHFEQNFRQ 300
  301 MLTMLASQSS GVPTGNHGLF HRYRIDALTI AANRRATHAT LKGSPGSAAV PLLKAIEGIA 360
  361 RSLNNLLERF HQSFFFYVIV SNDRYISIGD YMPALVALVA CAFLKAYLTW STL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.46
Match: 2afsA
Description: Crystal structure of the genetic mutant R54W of human glutaminyl cyclase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.30073863026596 bayes_pls_golite062009
peptidase activity 0.895011778331062 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.763798185754152 bayes_pls_golite062009
binding 0.374473226792137 bayes_pls_golite062009
nucleic acid binding 0.362145256746391 bayes_pls_golite062009
protein binding 0.192842853386021 bayes_pls_golite062009
transcription regulator activity 0.171364523459 bayes_pls_golite062009
DNA binding 0.0535456396545306 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [414-480]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PATNAELEKA AGWLREHEQE AELEENLEPD KFELPYGSVL IYLTATLLIG FLCNVLPLQQ  60
   61 YFLEIPM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [481-557]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAPLTTSVL SFLSLIGFVL PFVVVLPPGG LELLHVAFLL IYGCALIVIG LLNFALGLFA  60
   61 AVLTVPLVIA LETKEEN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [558-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SRSTLRNTIR LATLVMNPMM VVYVIVLAMT FYQFPELPVQ KIMLRAATAA MDASAYGLID  60
   61 SVIYGNWLYF VICTIFLPLW IICWTLSLSK RRDYADYLDF DESPSTSPQP QSKVKTN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle