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View Structure Prediction Details

Protein: XRCC1-PA
Organism: Drosophila melanogaster
Length: 614 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XRCC1-PA.

Description E-value Query
Range
Subject
Range
gi|70878103 - gi|70878103|gb|EAN91386.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71648919 - gi|71648919|ref|XP_813237.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
285.0 [0..64] [614..704]

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Predicted Domain #1
Region A:
Residues: [1-197]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPIALFKSVR EVSSEDAVHV AANLLKENAG KKWRTKAPGE KSAYVVLEFE EPQQITGIDI  60
   61 GNEHAAFIEV LVSRTGCQAD DFRELLLSSS FMTPIESKNS SNPNRVRCFS STSLAESALP 120
  121 EKWKLLQIVC TQPFNRHVPY GLSFVKVHVV AAAAPKVKSL VPQGVMQFGT FKLREESPDS 180
  181 ETDNQVNRFH SWKKQTQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1xnaA
Description: N-terminal domain of xrcc1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.385277722045402 bayes_pls_golite062009
catalytic activity 0.248020161559829 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [198-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKSPAISATS TAAAIRDAGS TALRRLSAGK VSSLAASPKT STSPSPVLNA LRSVSPTPLD  60
   61 AKPLDRNRAS LLFGDDDEDV KDAEVNA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [285-403]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKQRLSKHLE ADKDRRRLEQ EKERESRKKK SSRHSLDKSI SKEDKPPAKE HNSSSREKST  60
   61 AKEEKEQLRK EERSHSKEEK SRRKEKSKHD HRSSDTSNSK ESSRPTAQKR HSSPTAVAV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.14
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #4
Region A:
Residues: [404-516]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPAKKQKIVD TAIQYRPLNQ LLKGVVLVIS GIQNPDRADL RSKAVALGAK YKADWGSGCT  60
   61 HLICAFKNTP KYNQVKGKGK IVTRSWIEKC YELKKYLPWR RYALDTNDIG QPE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 2d8mA
Description: No description for 2d8mA was found.

Predicted Domain #5
Region A:
Residues: [517-614]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDEELCDEAT RPRRDSSKDD VAMLEDSKLT ALADQNDVEM NPDALSGIDT EDELQRVAEE  60
   61 NKTKKAKLRT TVKTKSQDIY EVSTDEEDYL ELKKKQID

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle