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View Structure Prediction Details

Protein: ph-p-PA
Organism: Drosophila melanogaster
Length: 1589 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ph-p-PA.

Description E-value Query
Range
Subject
Range
gi|2894095, gi|7... - pir||T13606 hypothetical protein 87B1.5 - fruit fly (Drosophila melanogaster), gi|2894095|emb|CAB10...
308.0 [0..1] [1589..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRRALKFMQ KRADTESDTT TPVSTTASQG ISASAILAGG TLPLKDNSNI REKPLHHNYN  60
   61 HNNNNSSQHS HSHQQQQQQQ VGGKQLERPL KCLETLAQKA GI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFDEKYDVAS PPHPGIAQQQ ATSGTGPATG SGSVTPTSHR HGTPPTGRRQ THTPSTPNRP  60
   61 SAPSTPNTNC N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [174-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIARHTSLTL EKAQNPGQQV AATTTVPLQI SPEQLQQFYA SNPYAIQVKQ EFPTHTTSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [233-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTELKHATN IMEVQQQLQL QQQLSEANGG GAASAGAGGA ASPANSQQSQ QQQHSTAIST  60
   61 MSPMQLAAAT GGVGGDWTQG RTVQLMQPST SFLYPQMIVS GNLLHPGGLG QQPIQVITAG 120
  121 KPFQGNGPQM LTTTTQNAKQ MIGGQAGFAG GNYATCIPTN HNQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [397-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQTVLFSPMN VISPQQQQNL LQSMAAAAQQ QQLTQQQQQF NQQQQQQLTQ QQQQLTAALA  60
   61 KVGVDAQGKL AQKVVQKVTT TSSAVQAATG PGSTGSTQTQ QVQQVQQQQQ QTTQTTQQCV 120
  121 QVSQSTLPVG VGGQSVQTAQ LLNAGQAQQM QIPWFLQNAA GLQPFGPNQI ILRNQPDGTQ 180
  181 GMFIQQQPAT QTLQTQQNQI IQCNVTQTPT KAR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [610-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLDALAPKQ QQQQQQVGTT NQTQQQQLAV ATAQLQQQQQ QLTAAALQRP GAPVMPHNGT  60
   61 QVRPASSVST QTAQNQSLLK AKMRNKQQPV RPALATLKTE IGQVAGQNKV VGHLTTVQQQ 120
  121 QQATNLQQVV NAAGNKMVVM STTGTPITLQ NGQTLHAATA AGVDKQQQQL QLFQKQQI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [788-910]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQQQQMLQQQ IAAIQMQQQQ AAVQAQQQQQ QQVSQQQQVN AQQQQAVAQQ QQAVAQAQQQ  60
   61 QREQQQQVAQ AQAQHQQALA NATQQILQVA PNQFITSHQQ QQQQQLHNQL IQQQLQQQAQ 120
  121 AQV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [911-1114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAQVQAQAQQ QQQQREQQQN IIQQIVVQQS GATSQQTSQQ QQHHQSGQLQ LSSVPFSVSS  60
   61 STTPAGIATS SALQAALSAS GAIFQTAKPG TCSSSSPTSS VVTITNQSST PLVTSSTVAS 120
  121 IQQAQTQSAQ VHQHQQLISA TIAGGTQQQP QGPPSLTPTT NPILAMTSMM NATVGHLSTA 180
  181 PPVTVSVTST AVTSSPGQLV LLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1115-1306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSGGGGSIP ATPTKETPSK GPTATLVPIG SPKTPVSGKD TCTTPKSSTP ATVSASVEAS  60
   61 SSTGEALSNG DASDRSSTPS KGATTPTSKQ SNAAVQPPSS TTPNSVSGKE EPKLATCGSL 120
  121 TSATSTSTTT TITNGIGVAR TTASTAVSTA STTTTSSGTF ITSCTSTTTT TTSSISNGSK 180
  181 DLPKAMIKPN VL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1307-1379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THVIDGFIIQ EANEPFPVTR QRYADKDVSD EPPKKKATMQ EDIKLSGIAS APGSDMVACE  60
   61 QCGKMEHKAK LKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1380-1473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRYCSPGCSR QAKNGIGGVG SGETNGLGTG GIVGVDAMAL VDRLDEAMAE EKMQTEATPK  60
   61 LSESFPILGA STEVPPMSLP VQAAISAPSP LAMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1474-1589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSPLSVALP TLAPLSVVTS GAAPKSSEVN GTDRPPISSW SVDDVSNFIR ELPGCQDYVD  60
   61 DFIQQEIDGQ ALLLLKEKHL VNAMGMKLGP ALKIVAKVES IKEVPPPGEA KDPGAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1pk1A
Description: Hetero SAM domain structure of Ph and Scm.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.633600780660145 bayes_pls_golite062009
protein binding 0.29861856894481 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle