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View Structure Prediction Details

Protein: ph-p-PA
Organism: Drosophila melanogaster
Length: 1589 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ph-p-PA.

Description E-value Query
Range
Subject
Range
gi|2894095, gi|7... - pir||T13606 hypothetical protein 87B1.5 - fruit fly (Drosophila melanogaster), gi|2894095|emb|CAB10...
308.0 [0..1] [1589..1]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRRALKFMQ KRADTESDTT TPVSTTASQG ISASAILAGG TLPLKDNSNI REKPLHHNYN  60
   61 HNNNNSSQHS HSHQQQQQQQ VGGKQLERPL KCLETLAQKA GI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [103-173]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFDEKYDVAS PPHPGIAQQQ ATSGTGPATG SGSVTPTSHR HGTPPTGRRQ THTPSTPNRP  60
   61 SAPSTPNTNC N

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [174-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIARHTSLTL EKAQNPGQQV AATTTVPLQI SPEQLQQFYA SNPYAIQVKQ EFPTHTTSG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [233-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTELKHATN IMEVQQQLQL QQQLSEANGG GAASAGAGGA ASPANSQQSQ QQQHSTAIST  60
   61 MSPMQLAAAT GGVGGDWTQG RTVQLMQPST SFLYPQMIVS GNLLHPGGLG QQPIQVITAG 120
  121 KPFQGNGPQM LTTTTQNAKQ MIGGQAGFAG GNYATCIPTN HNQS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [397-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQTVLFSPMN VISPQQQQNL LQSMAAAAQQ QQLTQQQQQF NQQQQQQLTQ QQQQLTAALA  60
   61 KVGVDAQGKL AQKVVQKVTT TSSAVQAATG PGSTGSTQTQ QVQQVQQQQQ QTTQTTQQCV 120
  121 QVSQSTLPVG VGGQSVQTAQ LLNAGQAQQM QIPWFLQNAA GLQPFGPNQI ILRNQPDGTQ 180
  181 GMFIQQQPAT QTLQTQQNQI IQCNVTQTPT KAR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [610-787]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLDALAPKQ QQQQQQVGTT NQTQQQQLAV ATAQLQQQQQ QLTAAALQRP GAPVMPHNGT  60
   61 QVRPASSVST QTAQNQSLLK AKMRNKQQPV RPALATLKTE IGQVAGQNKV VGHLTTVQQQ 120
  121 QQATNLQQVV NAAGNKMVVM STTGTPITLQ NGQTLHAATA AGVDKQQQQL QLFQKQQI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [788-910]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQQQQMLQQQ IAAIQMQQQQ AAVQAQQQQQ QQVSQQQQVN AQQQQAVAQQ QQAVAQAQQQ  60
   61 QREQQQQVAQ AQAQHQQALA NATQQILQVA PNQFITSHQQ QQQQQLHNQL IQQQLQQQAQ 120
  121 AQV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [911-1114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAQVQAQAQQ QQQQREQQQN IIQQIVVQQS GATSQQTSQQ QQHHQSGQLQ LSSVPFSVSS  60
   61 STTPAGIATS SALQAALSAS GAIFQTAKPG TCSSSSPTSS VVTITNQSST PLVTSSTVAS 120
  121 IQQAQTQSAQ VHQHQQLISA TIAGGTQQQP QGPPSLTPTT NPILAMTSMM NATVGHLSTA 180
  181 PPVTVSVTST AVTSSPGQLV LLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1115-1306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASSGGGGSIP ATPTKETPSK GPTATLVPIG SPKTPVSGKD TCTTPKSSTP ATVSASVEAS  60
   61 SSTGEALSNG DASDRSSTPS KGATTPTSKQ SNAAVQPPSS TTPNSVSGKE EPKLATCGSL 120
  121 TSATSTSTTT TITNGIGVAR TTASTAVSTA STTTTSSGTF ITSCTSTTTT TTSSISNGSK 180
  181 DLPKAMIKPN VL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1307-1379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 THVIDGFIIQ EANEPFPVTR QRYADKDVSD EPPKKKATMQ EDIKLSGIAS APGSDMVACE  60
   61 QCGKMEHKAK LKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [1380-1473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KRYCSPGCSR QAKNGIGGVG SGETNGLGTG GIVGVDAMAL VDRLDEAMAE EKMQTEATPK  60
   61 LSESFPILGA STEVPPMSLP VQAAISAPSP LAMP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1474-1589]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGSPLSVALP TLAPLSVVTS GAAPKSSEVN GTDRPPISSW SVDDVSNFIR ELPGCQDYVD  60
   61 DFIQQEIDGQ ALLLLKEKHL VNAMGMKLGP ALKIVAKVES IKEVPPPGEA KDPGAQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.0
Match: 1pk1A
Description: Hetero SAM domain structure of Ph and Scm.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.633600780660145 bayes_pls_golite062009
protein binding 0.29861856894481 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle