






| Protein: | Actbeta-PA |
| Organism: | Drosophila melanogaster |
| Length: | 946 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Actbeta-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
839.0 | [0..18] | [946..1] |
|
Region A: Residues: [1-219] |
1 11 21 31 41 51
| | | | | |
1 MRFAFDSNHS QSGAPFKGSR CFFNCQCICC RQGCCVVVVK CCCCFNLNCC NSLGSRKSFP 60
61 QPAAMRKKVA DLEVLRVSRF VAVILVLARW VTAVATLLTS CILLDIFSVP GQSGVADRSQ 120
121 ASSRTVHVSV PTTPNETPSS TSETKLKLLY GYTSYDINND QQVKSNNLCR VLCKSRNRKR 180
181 QRRRRRRRNH RRRRHRYTKR LHHLMQDNMS GFEQRLNFS
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [220-351] |
1 11 21 31 41 51
| | | | | |
1 DAKCQSLETN YGTNYDLVQG GKLFSQSERS LLVSPLREIE APWPAIHGSM RNCSKIKRNR 60
61 ANLIWLLIGL VWFEVKLINC NGISSSNYYA SNLESHKGCT LCHESGKPNI YTDKDNPHTD 120
121 YNIYNKYHSN NN
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [352-442] |
1 11 21 31 41 51
| | | | | |
1 FNKKTNQPHN NIAPSDEVRL ESIKRQILTK LGLSHKPNVS HPLPKQFIWE TIYRVDGGRM 60
61 IPNNAFGSSG KNLDQKTIKL RAFASPGSHL F
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [443-564] |
1 11 21 31 41 51
| | | | | |
1 NGRGGRTDQR SERDPSHHKY RSPFDFTFNI SKNNVYGKVL RNRSLERIDK KNSFLNGWTE 60
61 NRQLKINSQI ASMPIELKSH HNSSPKELKS GAVRKVNGIN GTQMNENALK KSTYPIDINH 120
121 SI
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [565-651] |
1 11 21 31 41 51
| | | | | |
1 DNKTHTGKNG EMSHNDYEYF NDYSVQTHDK NRYHEGRSSI GYQPAIHNIE YENQKGHHES 60
61 FADDHENIDH EDFFGNTQEI ITFAEEG
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [652-816] |
1 11 21 31 41 51
| | | | | |
1 TQYRQYRILE FSAQNRRVPS QKLSIRSAQI HIRIDKPHSL WIEKAKSLPE KHLLNTKRKW 60
61 GANKPHHRIK IWVFQLSTSI NITEKGIDKA IIFRASFQVD PKNLGWQKFD LTDTIREWYG 120
121 HTSHEKLRLL IDCTGCGGRY SLHLFQTSKL RGNSSDYLST NPNRP
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [817-946] |
1 11 21 31 41 51
| | | | | |
1 FLVLHTESSR TRRVRRRAVD CGGALNGQCC KESFYVSFKA LGWDDWIIAP RGYFANYCRG 60
61 DCTGSFRTPD TFQTFHAHFI EEYRKMGLMN GMRPCCAPIK FSSMSLIYYG DDGIIKRDLP 120
121 KMVVDECGCP
|
| Detection Method: | |
| Confidence: | 35.522879 |
| Match: | 1bmpA |
| Description: | BONE MORPHOGENETIC PROTEIN-7 |
Matching Structure (courtesy of the PDB):![]() |
|
| Term | Confidence | Notes |
| receptor binding | 3.67407540757291 | bayes_pls_golite062009 |
| growth factor activity | 3.00792386593701 | bayes_pls_golite062009 |
| binding | 2.18106161869951 | bayes_pls_golite062009 |
| receptor serine/threonine kinase binding | 2.01478614969692 | bayes_pls_golite062009 |
| protein binding | 2.01254413740256 | bayes_pls_golite062009 |
| transforming growth factor beta receptor binding | 1.87074199164241 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase binding | 1.87074199164241 | bayes_pls_golite062009 |
| cell surface binding | 1.71347296916502 | bayes_pls_golite062009 |
| type II transforming growth factor beta receptor binding | 1.60271967659465 | bayes_pls_golite062009 |
| vascular endothelial growth factor receptor binding | 1.43930353468665 | bayes_pls_golite062009 |
| cytokine activity | 1.29821582644036 | bayes_pls_golite062009 |
| platelet-derived growth factor receptor binding | 1.02262292046677 | bayes_pls_golite062009 |
| neurotrophin receptor binding | 0.81172494974121 | bayes_pls_golite062009 |
| heparin binding | 0.8114984612971 | bayes_pls_golite062009 |
| vascular endothelial growth factor receptor 2 binding | 0.808551053262969 | bayes_pls_golite062009 |
| glycosaminoglycan binding | 0.79853499343535 | bayes_pls_golite062009 |
| polysaccharide binding | 0.539968806788969 | bayes_pls_golite062009 |
| growth factor binding | 0.49508779568124 | bayes_pls_golite062009 |
| protein dimerization activity | 0.426935963412231 | bayes_pls_golite062009 |
| pattern binding | 0.377711019199199 | bayes_pls_golite062009 |
| hormone activity | 0.344797552374249 | bayes_pls_golite062009 |
| vascular endothelial growth factor receptor 1 binding | 0.250978411198471 | bayes_pls_golite062009 |
| platelet-derived growth factor binding | 0.186615795527151 | bayes_pls_golite062009 |
| protein homodimerization activity | 0.176088530902184 | bayes_pls_golite062009 |
| identical protein binding | 0.0880365341657661 | bayes_pls_golite062009 |