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View Structure Prediction Details

Protein: heph-PC, heph-PS...
Organism: Drosophila melanogaster
Length: 581 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for heph-PC, heph-PS....

Description E-value Query
Range
Subject
Range
gi|114674372 - gi|114674372|ref|XP_001172084.1| PREDICTED: polypyrimidine tract-binding protein 1 [Pan troglodytes]
303.0 [0..2] [581..391]

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Predicted Domain #1
Region A:
Residues: [1-139]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGSDELLSQ AAVMAPASDN NNQDLATKKA KLEPGTVLAG GIAKASKVIH LRNIPNESGE  60
   61 ADVIALGIPF GRVTNVLVLK GKNQAFIEMA DEISATSMVS CYTVTPPQMR GRMVYVQFSN 120
  121 HRELKTDQGH NNSTAHSDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.0
Match: 2ad9A
Description: Solution structure of Polypyrimidine Tract Binding protein RBD1 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.425042944899091 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [140-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVQSPASGSP LPLSAAANAT SNNANSSSDS NSAMGILQNT SAVNAGGNTN AAGGPNTVLR  60
   61 VIVESLMYPV SLDILHQIFQ RYGKVLKIVT FTKNNSFQAL IQYPDANSAQ HAKSLLDGQN 120
  121 IYNGCCTLRI DNSKLTALNV KYNNDKSRDF TNPALPPGEP GVDIMPTAGG LMNTNDLLLI 180
  181 AARQRPSLSG DKIVNGLGAP GVLPPFALGL GTPLTGGYNN ALPNLAAFSL ANSGALQTTA 240
  241 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.522879
Match: 2adbA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD2 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [380-581]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAMRGYSNVL LVSNLNEEMV TPDALFTLFG VYGDVQRVKI LYNKKDSALI QMAEPQQAYL  60
   61 AMSHLDKLRL WGKPIRVMAS KHQAVQLPKE GQPDAGLTRD YSQNPLHRFK KPGSKNYQNI 120
  121 YPPSATLHLS NIPSSCSEDD IKEAFTSNSF EVKAFKFFPK DRKMALLQLL SVEEAVLALI 180
  181 KMHNHQLSES NHLRVSFSKS NI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.522879
Match: 2adcA
Description: Solution structure of Polypyrimidine Tract Binding protein RBD34 complexed with CUCUCU RNA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 6.73097473547076 bayes_pls_golite062009
6.62953239642182 bayes_pls_golite062009
mRNA binding 5.29759606920196 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
snRNA binding 3.28448936696877 bayes_pls_golite062009
poly-pyrimidine tract binding 3.11990160533699 bayes_pls_golite062009
single-stranded RNA binding 2.93798024346416 bayes_pls_golite062009
U1 snRNA binding 2.26303528058407 bayes_pls_golite062009
structural molecule activity 1.29928829870122 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
mRNA 3'-UTR binding 0.591700155096213 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.425042944899091 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009
snoRNA binding 0.0568636182001701 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle