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View Structure Prediction Details

Protein: PH4alphaNE3-PA
Organism: Drosophila melanogaster
Length: 481 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PH4alphaNE3-PA.

Description E-value Query
Range
Subject
Range
P4HA1_PONPY - Prolyl 4-hydroxylase subunit alpha-1 precursor - Pongo pygmaeus (Orangutan)
gi|123981532, gi... - gi|123996359|gb|ABM85781.1| procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase...
gi|114631179, gi... - gi|114631187|ref|XP_001141043.1| PREDICTED: prolyl 4-hydroxylase, alpha I subunit isoform 12 [Pan tr...
P4HA1_PONAB - Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii GN=P4HA1 PE=2 SV=1
P4HA1 - prolyl 4-hydroxylase, alpha polypeptide I
527.0 [0..1] [480..5]

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Predicted Domain #1
Region A:
Residues: [1-153]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFCKVESTLN WESRQEFLDT ESAKMDLMQL DVELIDNLMN YAEKIDEKAS QLKRLAQELR  60
   61 QPLHSAKGRE EEYLGNPLHS FPLIRHMYQD WRYLEEFMKK PVGEEEIQFL RRKLPELPWQ 120
  121 VDTEEASVSI FRIAETYGMM PWDMANGLID NVR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.080922
Match: PF08336.2
Description: No description for PF08336.2 was found.

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [154-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FNSTLPALDC FEVAKMYFKW GYFKQALQWI TISKARMKEE YSGVYEVLGM NRQDVALLQA  60
   61 RCLVELDRRD EAHEVLLDQP DLADNSISLL DQFKANPYE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 1tjcA
Description: Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.534990536504941 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [253-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIDSSPKLGE GYKRLCRSSF SPNPSKLHCR YNSTTSAFLI LAPLKMEEIS LEPHIVVYHD  60
   61 ILPDKDIQQL ITLAEPLLKP TEMFDDNKNE ARSSYRTPLG GPLLDSLTQR MRDITGLQIR 120
  121 QGNPINIIKY GFGAPYTNYY DFFKKRNSES KGFGDRMATF MFYLNDAPYG GATVFPRLNV 180
  181 KVPAERGKVL FWYNLNGDTH DMEPTTMHAA CPVFHGSKWV MTAWIHEYD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.95
Match: 2hbtA
Description: No description for 2hbtA was found.

YRC Informatics Platform - Version 3.0
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