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View Structure Prediction Details

Protein: gi|24651422, gi|...
Organism: Drosophila melanogaster
Length: 505 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24651422, gi|....

Description E-value Query
Range
Subject
Range
gi|109488103 - gi|109488103|ref|XP_340799.3| PREDICTED: similar to Prolyl 4-hydroxylase alpha-2 subunit precursor (...
562.0 [0..2] [500..128]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVVFSVLWL LQLFLLVESV AGANFARGEE QLQALLDTET QLIDGLRDYI ERLERQLEEI  60
   61 RRETSAIEEI HSQVDSVEEY MGNPLNVFGI LKRFESVWPG LEQKANATLE MVFGERLSDR 120
  121 QLTLPSEEDY EESLNHLLHL QSVYELDSNS LSLGVVNGFK LG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 51.0
Match: PF08336.2
Description: No description for PF08336.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [163-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSMSWGDCLE VARKSDFPVA RFWLESALEK LPSASENSTE SQRERESGRV HILEATLNIE  60
   61 YRAGELSRAL ATAEELLLLL PMNQGIQKAK RKIEKAMAKK ELPKGRGQKS KAKKQISKST 120
  121 EQLLIEEICR GAKQQVTTGS RFNHCQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1tjcA
Description: Crystal structure of peptide-substrate-binding domain of human type I collagen prolyl 4-hydroxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.14253214573541 bayes_pls_golite062009
protein binding 1.65083457326273 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [310-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGSSPWLLLQ PSRLEPVSSD PYIVLHHDVL TPKESNELLQ LIDEEEDTKG VSYQSLKLSK  60
   61 LAQKKLGRIS RLLGLEILEL DPWTGRRHGH EHITKLEHSS ELKHVARLML NAPGMGGAVV 120
  121 FPQLELAVNV PRGSLLHWRT RFAGGSSSEW DYRSGQAICP VLLGVQLSVI ACQSNVLRDT 180
  181 LYGPRGQDSI DVGSEA

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.13
Match: 2hbtA
Description: No description for 2hbtA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle