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View Structure Prediction Details

Protein: PH4alphaEFB-PA
Organism: Drosophila melanogaster
Length: 550 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PH4alphaEFB-PA.

Description E-value Query
Range
Subject
Range
gi|109488103 - gi|109488103|ref|XP_340799.3| PREDICTED: similar to Prolyl 4-hydroxylase alpha-2 subunit precursor (...
479.0 [0..2] [545..129]

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Predicted Domain #1
Region A:
Residues: [1-289]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAADWRLMLL LGILLLVGGP ANGEVYTALA EMEELLETES VLITNLEGYI RVQEDKLNFL  60
   61 KNKMDEYQRE HSDASHDITA YVSNPINAYL LTKRLTTDWR QVENLMEHDV GTDFLQNITQ 120
  121 YRSLLKFPSD EDLNGAAVAL LRLQDTYQLD TSSVARGKLN GIQYSTEMSS DDCFELGRQS 180
  181 YVNHDYYHTV LWMNEAMARM LEEPTNHTQS FTKADILEYL AFSTYKEGNI ESALTMTNEL 240
  241 LQLLPHHERA NGNKRFYEKE IAQQLQLRKM KGDDGTDEMP KSDLPVAKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.30103
Match: 1w3bA
Description: The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
procollagen-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
procollagen-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline dioxygenase activity 7.0422525853653 bayes_pls_golite062009
peptidyl-proline 4-dioxygenase activity 7.0422525853653 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 5.01373106146099 bayes_pls_golite062009
binding 2.09193012129784 bayes_pls_golite062009
protein binding 1.52807685989528 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 0.534990536504941 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [290-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPAIFDMTER RAYEMLCRGE LKPSPSDLRS LRCRYVTNRV PFLRLGPLKL EEVHADPYIV  60
   61 IYHDAMYDSE IDLIKRMARP RFRRATVQNS VTGALETANY RISKSAWLKT QEDRVIETVV 120
  121 QRTADMTGLD MDSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 2gw1A
Description: No description for 2gw1A was found.

Predicted Domain #3
Region A:
Residues: [424-550]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EELQVVNYGI GGHYEPHFDF ARKEEQRAFE GLNLGNRIAT VLFYMSDVEQ GGATVFTSLH  60
   61 TALFPKKGTA AFWMNLHRDG QGDVRTRHAA CPVLTGTKWV SNKWIHERGQ EFRRPCDLEE 120
  121 DHGEFAI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.02
Match: 2hbtA
Description: No description for 2hbtA was found.

YRC Informatics Platform - Version 3.0
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