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View Structure Prediction Details

Protein: CG7609-PA
Organism: Drosophila melanogaster
Length: 598 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7609-PA.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
654.0 [0..13] [597..1167]

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Predicted Domain #1
Region A:
Residues: [1-531]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDSVEDTST ISLRICLEGH ANALALNKDN NQIALAGRSL LKVYSINSNG FTESCNMRGK  60
   61 NQNLSYSAND VAWSTLDSNL LATAATNGVV SVWDLSKFGR QKQLLVYNEH ERTAHTVTFH 120
  121 SSEPNILISG SQDGTIKCFD IRSDKSINTY FCNSESVRDV KFSPHTQNIF SAVSENGTVQ 180
  181 LWDMRKWDKC MVQFTAHYGP VYTCDWHPTR NWLATGSRDK QIKVWNMDGR PGLEHTIHTI 240
  241 AVVGRVKWRP ERTYHIASCA LVVDYSVHVW DIRRPYIPFA SFNEHTNVTT GIAWQGSDSH 300
  301 CLLSISKDST IYKHAFKDAT RPALKANAQG ASLGRFGDIS FANKIKEYEP KTSGASNTKS 360
  361 SSFIRRKTNV AGSIQFHLDH SKMYKFMVND TFSGYPLSES VSRPTQEHES FIGCARELVI 420
  421 SGKKLSELCE HNAEVSKKYG KHNATTLWNF IKLFYGSNHF EPPFEHRSSF SNQKNPMNSR 480
  481 RATQVASDWP QQRTELGQDL NGNTPETAHE IDVANVDDDT LGSSGVEHPP T

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.30103
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
binding 2.2778252170547 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
peroxisome targeting sequence binding 1.73465159850484 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
protein binding 1.24173112731149 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
nucleic acid binding 0.693814013902061 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
cytoskeletal protein binding 0.359536347486199 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transcription regulator activity 0.190100099674138 bayes_pls_golite062009
chromatin binding 0.145491963066342 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
0.0248988265652406 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [532-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSVILSETQI ISEITFDNFE LLRNGFIYVG PTECPKALAF PALHHDVQAA RPQLDLKASD  60
   61 HEKSPVS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.522879
Match: 1p22A
Description: F-box/WD-repeat protein 1 (beta-TRCP1)
Matching Structure (courtesy of the PDB):

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