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View Structure Prediction Details

Protein: CG5948-PA
Organism: Drosophila melanogaster
Length: 270 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5948-PA.

Description E-value Query
Range
Subject
Range
gi|54638935, gi|... - gi|54638935|gb|EAL28337.1| GA19252-PA [Drosophila pseudoobscura], gi|125776182|ref|XP_001359193.1| G...
236.0 [0..1] [246..1]
gi|218564 - gi|218564|dbj|BAA14373.1| unnamed protein product [Schizosaccharomyces pombe]
191.0 [0..94] [258..3]
gi|5353561 - gi|5353561|gb|AAD42179.1| superoxide dismutase/HCV major epitope fusion protein [synthetic construct...
187.0 [0..94] [248..4]
gi|74203229 - gi|74203229|dbj|BAE26286.1| unnamed protein product [Mus musculus]
187.0 [0..19] [258..22]
SODC_MACMU - Superoxide dismutase [Cu-Zn] OS=Macaca mulatta GN=SOD1 PE=2 SV=3
SODC_MACFA - Superoxide dismutase [Cu-Zn] OS=Macaca fascicularis GN=SOD1 PE=2 SV=3
gi|23503516 - gi|23503516|dbj|BAC20348.1| Cu,Zn-superoxide dismutase [Macaca fuscata]
SODC_MACFU - Superoxide dismutase [Cu-Zn] OS=Macaca fuscata fuscata GN=SOD1 PE=2 SV=3
175.0 [0..94] [246..4]
SODC_CALJA - Superoxide dismutase [Cu-Zn] OS=Callithrix jacchus GN=SOD1 PE=2 SV=3
174.0 [0..94] [246..4]
SODC_HYLLA - Superoxide dismutase [Cu-Zn] OS=Hylobates lar GN=SOD1 PE=2 SV=3
173.0 [0..94] [246..4]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIKLILALV IGYGGIFAPG SAQNLLDRLR PVNMTRFDDG IKVVSGTKVK RYERLTVPLG  60
   61 GPVGIPGAAG LLGPLLPPQP SYLGYTYQLV PQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WQAGAKLMGD GEGAGVAGMI SFVQLPYNSD IRVTINVTGL PPGKHALHIH TFGDLSDGCK  60
   61 STGGQFPNNF LGNVDTKDDG SISAVFQSIY LQLFGINGIV GRSIVIHSKA IDLNTALNAE 120
  121 VFSSSLQAMP NPLAYQNEEN SLGPAIACGV ISIMSTAASS SGMATAAPAP PAMENPEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1hl4A
Description: Cu,Zn superoxide dismutase, SOD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein phosphatase 2B binding 13.5719110466797 bayes_pls_golite062009
superoxide dismutase activity 12.1093323949609 bayes_pls_golite062009
oxidoreductase activity, acting on superoxide radicals as acceptor 12.1093323949609 bayes_pls_golite062009
chaperone binding 5.11696266714142 bayes_pls_golite062009
superoxide dismutase copper chaperone activity 4.90125496493753 bayes_pls_golite062009
copper ion binding 4.51765925795625 bayes_pls_golite062009
protein phosphatase binding 3.26481550276071 bayes_pls_golite062009
phosphatase binding 3.1414149853516 bayes_pls_golite062009
transition metal ion binding 2.451533032488 bayes_pls_golite062009
binding 2.28211284921339 bayes_pls_golite062009
enzyme binding 1.82618630359051 bayes_pls_golite062009
metal ion binding 1.79413011653575 bayes_pls_golite062009
cation binding 1.79413011653575 bayes_pls_golite062009
ion binding 1.78699219376941 bayes_pls_golite062009
catalytic activity 1.09233965765942 bayes_pls_golite062009
protein binding 0.916153188966515 bayes_pls_golite062009
copper ion transmembrane transporter activity 0.658369569046781 bayes_pls_golite062009
metallochaperone activity 0.515959593535099 bayes_pls_golite062009
copper chaperone activity 0.412497194733789 bayes_pls_golite062009
ion transmembrane transporter activity 0.32642292951469 bayes_pls_golite062009
cation transmembrane transporter activity 0.262312399748454 bayes_pls_golite062009
zinc ion binding 0.25600715352161 bayes_pls_golite062009
antioxidant activity 0.240491838042064 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle