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View Structure Prediction Details

Protein: CG5948-PA
Organism: Drosophila melanogaster
Length: 270 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG5948-PA.

Description E-value Query
Range
Subject
Range
gi|54638935, gi|... - gi|54638935|gb|EAL28337.1| GA19252-PA [Drosophila pseudoobscura], gi|125776182|ref|XP_001359193.1| G...
236.0 [0..1] [246..1]
gi|218564 - gi|218564|dbj|BAA14373.1| unnamed protein product [Schizosaccharomyces pombe]
191.0 [0..94] [258..3]
gi|5353561 - gi|5353561|gb|AAD42179.1| superoxide dismutase/HCV major epitope fusion protein [synthetic construct...
187.0 [0..94] [248..4]
gi|74203229 - gi|74203229|dbj|BAE26286.1| unnamed protein product [Mus musculus]
187.0 [0..19] [258..22]
SODC_MACMU - Superoxide dismutase [Cu-Zn] OS=Macaca mulatta GN=SOD1 PE=2 SV=3
SODC_MACFA - Superoxide dismutase [Cu-Zn] OS=Macaca fascicularis GN=SOD1 PE=2 SV=3
gi|23503516 - gi|23503516|dbj|BAC20348.1| Cu,Zn-superoxide dismutase [Macaca fuscata]
SODC_MACFU - Superoxide dismutase [Cu-Zn] OS=Macaca fuscata fuscata GN=SOD1 PE=2 SV=3
175.0 [0..94] [246..4]
SODC_CALJA - Superoxide dismutase [Cu-Zn] OS=Callithrix jacchus GN=SOD1 PE=2 SV=3
174.0 [0..94] [246..4]
SODC_HYLLA - Superoxide dismutase [Cu-Zn] OS=Hylobates lar GN=SOD1 PE=2 SV=3
173.0 [0..94] [246..4]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIKLILALV IGYGGIFAPG SAQNLLDRLR PVNMTRFDDG IKVVSGTKVK RYERLTVPLG  60
   61 GPVGIPGAAG LLGPLLPPQP SYLGYTYQLV PQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.643 d.48.1 RecA protein, C-terminal domain
View Download 0.492 d.50.3 PI-Pfui intein middle domain
View Download 0.349 g.37.1 C2H2 and C2HC zinc fingers
View Download 0.307 d.9.2 Description not found.
View Download 0.287 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain

Predicted Domain #2
Region A:
Residues: [93-270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WQAGAKLMGD GEGAGVAGMI SFVQLPYNSD IRVTINVTGL PPGKHALHIH TFGDLSDGCK  60
   61 STGGQFPNNF LGNVDTKDDG SISAVFQSIY LQLFGINGIV GRSIVIHSKA IDLNTALNAE 120
  121 VFSSSLQAMP NPLAYQNEEN SLGPAIACGV ISIMSTAASS SGMATAAPAP PAMENPEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 1hl4A
Description: Cu,Zn superoxide dismutase, SOD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein phosphatase 2B binding 13.5719110466797 bayes_pls_golite062009
superoxide dismutase activity 12.1093323949609 bayes_pls_golite062009
oxidoreductase activity, acting on superoxide radicals as acceptor 12.1093323949609 bayes_pls_golite062009
chaperone binding 5.11696266714142 bayes_pls_golite062009
superoxide dismutase copper chaperone activity 4.90125496493753 bayes_pls_golite062009
copper ion binding 4.51765925795625 bayes_pls_golite062009
protein phosphatase binding 3.26481550276071 bayes_pls_golite062009
phosphatase binding 3.1414149853516 bayes_pls_golite062009
transition metal ion binding 2.451533032488 bayes_pls_golite062009
binding 2.28211284921339 bayes_pls_golite062009
enzyme binding 1.82618630359051 bayes_pls_golite062009
metal ion binding 1.79413011653575 bayes_pls_golite062009
cation binding 1.79413011653575 bayes_pls_golite062009
ion binding 1.78699219376941 bayes_pls_golite062009
catalytic activity 1.09233965765942 bayes_pls_golite062009
protein binding 0.916153188966515 bayes_pls_golite062009
copper ion transmembrane transporter activity 0.658369569046781 bayes_pls_golite062009
metallochaperone activity 0.515959593535099 bayes_pls_golite062009
copper chaperone activity 0.412497194733789 bayes_pls_golite062009
ion transmembrane transporter activity 0.32642292951469 bayes_pls_golite062009
cation transmembrane transporter activity 0.262312399748454 bayes_pls_golite062009
zinc ion binding 0.25600715352161 bayes_pls_golite062009
antioxidant activity 0.240491838042064 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle