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View Structure Prediction Details

Protein: FBpp0292528, CG1...
Organism: Drosophila melanogaster
Length: 590 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0292528, CG1....

Description E-value Query
Range
Subject
Range
gi|114583147, gi... - gi|114583147|ref|XP_001150830.1| PREDICTED: similar to 5-aminoimidazole-4-carboxamide-1-beta-D-ribon...
789.0 [0..1] [590..1]

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Predicted Domain #1
Region A:
Residues: [1-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKIALLS VSDKTGLLDL GKSLVALGFD LVASGGTATS LRGAGLKVRD VSEITGAPEM  60
   61 LGGRVKTLHP AVHAGILSRT TDSDLADMRK QGFDLIQLVV CNLYPFASTV AKPDVTLADA 120
  121 VENIDIGGVT LLRAAAKNHQ RVTVVCEAVD YDRVLSELKA SGNTTVETRQ ALALKAFTHT 180
  181 ATYDDAISDY FRKQYGSGVS QLPLRYGMNP HQKPAQLYTQ LAKLPLTVLN ASPGFINLCD 240
  241 ALNGWQLVRE LKKALQLPAA TSFKHVSPAG AAVGVPLNPA QAKLCMVDDL YEQLTPLATA 300
  301 YARARGADRM SSFGDFVALS DVCDVVTARI ISREVSDGII AAGYEPEALE ILKKKKNGGY 360
  361 CILQMDPNYE PSAVERKTIF GLTLEQKRND AVIDASLFSN VVSKRGPLPE VAVRDLIVAT 420
  421 IALKYTQSNS VCYARDGQVV GIGAGQQSRI HCTRLAGEKA DNWWLRQHPS VAGMKFKAGV 480
  481 KRAEISNAID NYVNGTVGKD MPLSQFEGMF DKAPAQLTSE QKVEWLKQLS GVALGSDAFF 540
  541 PFRDNIDRAS LSGVSYIASP AGSTNDAGVI AACDEHGIIM AHTNLRLFHH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1p4rA
Description: Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
IMP cyclohydrolase activity 2.44338227123463 bayes_pls_golite062009
phosphoribosylaminoimidazolecarboxamide formyltransferase activity 2.17104645465987 bayes_pls_golite062009
formate dehydrogenase activity 2.1190774640451 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1.79965948308471 bayes_pls_golite062009
catalytic activity 1.70756445127105 bayes_pls_golite062009
hydroxymethyl-, formyl- and related transferase activity 1.51378035087272 bayes_pls_golite062009
binding 1.21541060770936 bayes_pls_golite062009
glycine hydroxymethyltransferase activity 1.19388272840449 bayes_pls_golite062009
deaminase activity 1.16510523659661 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.03324558866637 bayes_pls_golite062009
cytidine deaminase activity 0.870445440530128 bayes_pls_golite062009
oxidoreductase activity 0.738911503392967 bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates 0.344740566585736 bayes_pls_golite062009
electron carrier activity 0.178707818321223 bayes_pls_golite062009
protein binding 0.072557222523031 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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