| Protein: | SMC1-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1238 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SMC1-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
309.0 | [0..1] | [1238..1] |
|
Region A: Residues: [1-94] |
1 11 21 31 41 51
| | | | | |
1 MTEEDDDVAQ RVATAPVRKP DDETAFLEYI EMENFKSYRG HIVVGPLKQF NAVIGPNGSG 60
61 KSNFMDAISF VMGEKTSSLR VKRLNDLIHG SSIG
|
| Detection Method: |  |
| Confidence: | 23.69897 |
| Match: | 1w1wA |
| Description: | Sc Smc1hd:Scc1-C complex, ATPgS |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [95-434] |
1 11 21 31 41 51
| | | | | |
1 KPVSRSCYVT AKFVLNEERH MDFQRAVIGG SSEYRINGES VSSSTYLNKL EKIGINVKAK 60
61 NFLVFQGAVE NIAMKTPKER TALFEEISGS GLLKDDYNRL KQEMIVAEEE TQFTYQKKKG 120
121 IAAERKEAKH EKMEADRYTR LQNEYNEKQV EYQLFRLFHV ERDIRKFTSD LEVRQQEVKA 180
181 VEQRKEAADE ILREKKKDAG KITRDLAKID QEIREFETQM NKRRPLYIKA KEKVTHCKKK 240
241 LISLQKTLET AREADNAHQS DIRKLEKQLA DVEALKKRFE DEIENESQRR GKSVNMEEGL 300
301 VQEYDRLKQE AEATATQYRS ELDSVNREQK SEQDTLDGET
|
| Detection Method: | |
| Confidence: | 15.221849 |
| Match: | 1i84S |
| Description: | Heavy meromyosin subfragment |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [435-730] |
1 11 21 31 41 51
| | | | | |
1 NRRASVEESF KKLTLQREEA VKRRDKLMDH IKSSQAALEE QNRIKDELRR DVGTSKEKIA 60
61 EKQRELEDVR DQLGDAKSDK HEDARRKKKQ EVVELFKKQV PGVYDRMINM CQPTHKRYNV 120
121 AVTKVLGKFM EAIIVDTEKT ARHCIQILKE QMLEVETFLP LDYLQVKPLK ERLRNISDPR 180
181 NVRLVFDVLK FEPQEIERAV LFATGNALVC ETPEDAMKVA YEIDRSRFDA LALDGTFYQK 240
241 SGLISGGSHD LARKAKRWDE KHMAQLKMQK ERLQEELKEL VKKSRKQSEL ATVESQ
|
| Detection Method: | |
| Confidence: | 4.35 |
| Match: | 1gxlA |
| Description: | Smc hinge domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.91859588671053 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.23709457794394 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16063754070957 | bayes_pls_golite062009 |
| DNA binding | 1.10832034923143 | bayes_pls_golite062009 |
| protein binding | 1.02696508439754 | bayes_pls_golite062009 |
| DNA secondary structure binding | 1.02239440262162 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.999818859536395 | bayes_pls_golite062009 |
| protein heterodimerization activity | 0.558475595998159 | bayes_pls_golite062009 |
| catalytic activity | 0.265320175609019 | bayes_pls_golite062009 |
| protein dimerization activity | 0.108132520107784 | bayes_pls_golite062009 |
|
Region A: Residues: [731-1090] |
1 11 21 31 41 51
| | | | | |
1 IKGLENRLKY SMVDLESSKK SISQYDNQLQ QVQSQLDEFG PKILEIERRM QNREEHIQEI 60
61 KENMNNVEDK VYASFCRRLG VKNIRQYEER ELVMQQERAR KRAEFEQQID SINSQLDFEK 120
121 QKDTKKNVER WERSVQDEED ALEGLKLAEA RYLKEIDEDK EKMEKFKQDK QAKKQAVDDM 180
181 EEDISKARKD VANLAKEIHN VGSHLSAVES KIEAKKNERQ NILLQAKTDC IVVPLLRGSL 240
241 DDAVRQSDPD VPSTSAAMEN IIEVDYSSLP REYTKLKDDS AFKKTHEMLQ KDLQSKLDVL 300
301 ERIQTPNMKA LQKLDAVTEK VQSTNEEFEN ARKKAKRAKA AFERVKNERS SRFVACCQHI 360
361
|
| Detection Method: | |
| Confidence: | 2.16 |
| Match: | 1c1gA |
| Description: | Tropomyosin |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [1091-1238] |
1 11 21 31 41 51
| | | | | |
1 SDAIDGIYKK LARNEAAQAY IGPDNPEEPY LDGINYNCVA PGKRFQPMNN LSGGEKTIAA 60
61 LALLFSTHSF HPAPFFVLDE IDAALDNTNI GKVASYIRDH TTNLQTIVIS LKEEFYGHAD 120
121 ALVGITPGEG DCLVSNVYIM DLTTFEDT
|
| Detection Method: | |
| Confidence: | 15.154902 |
| Match: | 1xexB |
| Description: | Structural biochemistry of ATP-driven dimerization and DNA stimulated activation of SMC ATPases. |
Matching Structure (courtesy of the PDB): |
|
