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View Structure Prediction Details

Protein: CG10214-PA
Organism: Drosophila melanogaster
Length: 211 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG10214-PA.

Description E-value Query
Range
Subject
Range
gi|109108727 - gi|109108727|ref|XP_001087552.1| PREDICTED: similar to Oligoribonuclease, mitochondrial precursor (S...
gi|90080269 - gi|90080269|dbj|BAE89616.1| unnamed protein product [Macaca fascicularis]
195.0 [0..5] [210..11]
gi|55637001 - gi|55637001|ref|XP_508768.1| PREDICTED: similar to CGI-114 protein isoform 2 [Pan troglodytes]
REXO2 - REX2, RNA exonuclease 2 homolog (S. cerevisiae)
194.0 [0..5] [210..11]
HGNC:17851|MIM:6... - RNA exonuclease 2 homolog (S. cerevisiae)
REXO2 - REX2, RNA exonuclease 2 homolog (S. cerevisiae)
gi|117646830, gi... - gi|208965440|dbj|BAG72734.1| REX2, RNA exonuclease 2 homolog [synthetic construct], gi|117646830|emb...
194.0 [0..5] [210..11]
ORN_BOVIN - Oligoribonuclease, mitochondrial OS=Bos taurus GN=REXO2 PE=2 SV=1
190.0 [0..5] [210..11]
gi|37590357, gi|... - gi|41152197|ref|NP_957038.1| small fragment nuclease [Danio rerio], gi|37590357|gb|AAH59540.1| Small...
188.0 [0..30] [211..1]
gi|74196748 - gi|74196748|dbj|BAE43110.1| unnamed protein product [Mus musculus]
187.0 [0..5] [210..11]
ORN_RAT - Oligoribonuclease, mitochondrial OS=Rattus norvegicus GN=Rexo2 PE=2 SV=1
187.0 [0..5] [210..11]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLAHLRRVGL SLNRQIRSHI AFNSNDRMSS TCGLDTDIVW MDLEMTGLDI EKDKILEVAC  60
   61 IITDQDLNVK SEGPCFAINH PQEVYDSMNE WCMKHHYNSG LIDRCKSSDV NLEEASNLVL 120
  121 SYLEKNIPKR ACPLGGNSVY TDRLFIMKFM PLVDAYLHYR IVDVSTIKEL AKRWHPAILD 180
  181 SAPKKSFTHR SLDDIRESIK ELAYYKANLF K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.522879
Match: 1ytaA
Description: Crystal Structure of Oligoribonuclease, the lone essential exoribonuclease in Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 4.81599779544001 bayes_pls_golite062009
exoribonuclease activity 3.01417328311605 bayes_pls_golite062009
ribonuclease H activity 2.91966688044755 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 2.89077854960958 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.70794511869438 bayes_pls_golite062009
nuclease activity 2.65398446409354 bayes_pls_golite062009
endonuclease activity 2.63074055051349 bayes_pls_golite062009
endoribonuclease activity 2.59247838057313 bayes_pls_golite062009
hydrolase activity 2.41899414621161 bayes_pls_golite062009
transcription regulator activity 2.20855917457806 bayes_pls_golite062009
binding 1.8781442498221 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 1.74431545836806 bayes_pls_golite062009
nucleic acid binding 1.72558334058697 bayes_pls_golite062009
DNA binding 1.62101283948059 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.59628511603826 bayes_pls_golite062009
exonuclease activity 1.4327316829508 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.42069917818896 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
1.18236432793831 bayes_pls_golite062009
transcription factor activity 0.971926865662649 bayes_pls_golite062009
3'-5' exonuclease activity 0.86862629020506 bayes_pls_golite062009
RNA binding 0.750194803368593 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.389326716045122 bayes_pls_golite062009
transcription activator activity 0.104967281174106 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle